对墨西哥坎佩切州（尤卡坦半岛）为期两年的皮肤利什曼病研究。

Study of cutaneous leishmaniasis in the State of Campeche (Yucatan Peninsula), Mexico, over a period of two years.

作者信息

Hernández-Rivera Mirsha Pamela, Hernández-Montes Omar, Chiñas-Pérez Adelaido, Batiza-Avelar Juan Miguel, Sánchez-Tejeda Gustavo, Wong-Ramírez Carlos, Monroy-Ostria Amalia

机构信息

Escuela Nacional de Ciencias Biologicas, Instituto Politécnico Nacional, México, Distrito Federal, México.

Honorable Ayuntamiento de Calakmul, Campeche, México.

出版信息

Salud Publica Mex. 2015 Jan-Feb;57(1):58-65. doi: 10.21149/spm.v57i1.7403.

DOI:10.21149/spm.v57i1.7403

PMID:25629280

Abstract

OBJECTIVE

To study cutaneous leishmaniasis (CL), in the Calakmul municipality of the Campeche State, during two years.

MATERIALS AND METHODS

Individuals with skin lesions were evaluated. Aspirates taken from the lesions were cultured, PCR was performed to diagnose the Leishmania species.

RESULTS

The culture detected 42% of the samples. PCR diagnosed CL in 76% of the samples; of those 38% were from children and 62% from adults. 89% of the patients were infected with L. mexicana; 14.4% with Mexican strains of L. mexicana; 7% with L. braziliensis; 3.6% with L. mexicana and L. braziliensis. The most affected villages with CL were Dos Lagunas Sur with 12.3%, La Mancolona with 6.5% and La Guadalupe with 2.2% of prevalence, respectively. After the treatment with Glucantime, 96% of the patients were healed.

CONCLUSION

CL is an important public health concern in Calakmul, and the parasite causing it belongs to Leishmania mexicana and Leishmania braziliensis complexes.

摘要

目的

对坎佩切州卡拉科姆尔市的皮肤利什曼病（CL）进行为期两年的研究。

材料与方法

对有皮肤病变的个体进行评估。从病变处采集的抽吸物进行培养，采用聚合酶链反应（PCR）诊断利什曼原虫种类。

结果

培养法检测出42%的样本。PCR诊断出76%的样本患有CL；其中38%为儿童，62%为成人。89%的患者感染了墨西哥利什曼原虫；14.4%感染了墨西哥利什曼原虫的墨西哥菌株；7%感染了巴西利什曼原虫；3.6%同时感染了墨西哥利什曼原虫和巴西利什曼原虫。CL感染率最高的村庄分别是南多斯拉古纳斯村（12.3%）、拉曼科洛纳村（6.5%）和拉瓜达卢佩村（2.2%）。使用葡糖胺治疗后，96%的患者痊愈。