Author Affiliations: National Evidence-Based Healthcare Collaborating Agency, Seoul, South Korea (Ms Jung); College of Nursing, University of Massachusetts at Amherst (Dr Chung); Chung-Ang University, Red Cross College of Nursing, Seoul, South Korea (Dr Son).
Cancer Nurs. 2021;44(6):E414-E428. doi: 10.1097/NCC.0000000000000888.
Physical activity (PA) has been shown to improve total mortality and colorectal-specific mortality risk; however, colorectal cancer (CRC) survivors have lower rates of PA compared with survivors with other types of cancers.
To examine the effect of PA interventions on CRC survivors.
A systematic review and meta-analysis were conducted to identify randomized controlled trials that met the inclusion criteria, which included an intervention designed to increase PA and more than 1 outcome of interest. Random effects of the meta-analyses were performed using Review Manager 5.3.
Eight publications representing 7 randomized controlled trials of 803 participants were identified. All studies used a combination of behavioral change methods. Physical activity interventions significantly improved disease-specific quality of life, PA level, and maximum amount of oxygen and did not show significant improvements for fatigue and body mass index among CRC survivors.
We provided evidence that PA interventions were effective in improving disease-specific quality of life, PA level, and maximum amount of oxygen; however, they did not improve fatigue and body mass index. Further randomized controlled trials are needed to determine the optimal mode of delivering PA intervention for CRC survivors.
As the survival rate of patients with CRC increases, survivors of CRC need to increase PA in a community setting after completing primary treatments. Effective and efficient modes of PA intervention delivery could improve health-related outcomes and address specific barriers for CRC survivors.
身体活动（PA）已被证明可降低全因死亡率和结直肠癌特异性死亡率风险；然而，与其他类型癌症的幸存者相比，结直肠癌（CRC）幸存者的身体活动水平较低。
评估身体活动干预对 CRC 幸存者的影响。
系统检索和荟萃分析旨在确定符合纳入标准的随机对照试验，包括旨在增加身体活动且有 1 个以上感兴趣结局的干预措施。使用 Review Manager 5.3 进行荟萃分析的随机效应。
确定了 8 篇文献，代表 7 项随机对照试验共 803 名参与者。所有研究均采用了行为改变方法的组合。身体活动干预可显著改善疾病特异性生活质量、身体活动水平和最大摄氧量，而对疲劳和身体质量指数无显著改善。
我们提供了证据表明，身体活动干预措施可有效改善疾病特异性生活质量、身体活动水平和最大摄氧量；然而，它们并不能改善疲劳和身体质量指数。需要进一步的随机对照试验来确定针对 CRC 幸存者的最佳身体活动干预模式。
随着 CRC 患者的生存率提高，CRC 幸存者在完成主要治疗后需要在社区环境中增加身体活动。有效的、高效的身体活动干预措施的提供方式可以改善与健康相关的结局，并解决 CRC 幸存者的具体障碍。
