Azizbeigi Kamal, Azarbayjani Mohammad Ali, Atashak Sirvan, Stannard Stephen R
a Exercise Physiology Department, Faculty of Physical Education , Islamic Azad University, Sannadaj Branch , Iran.
Res Sports Med. 2015;23(1):73-87. doi: 10.1080/15438627.2014.975807.
This study was designed to examine the effect of moderate (MR) and high resistance (HR) training on systemic inflammation and circulating enzymatic antioxidant activity. Thirty males were assigned to HR (n = 10), MR (n = 10), or control (C; n = 10) groups. Resistance training was performed for eight weeks. Activities of superoxide dismutase (SOD), glutathione peroxidase (GPX), creatine kinase (CK), and concentrations of malondialdehyde (MDA), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) were measured before and after training in plasma. The results show increased SOD activity in MR (p = 0.026) and HR (p = 0.044) groups. GPX activity in HR (p = 0.012) and MR (p = 0.037) increased significantly more than in C. Whilst a significant reduction in MDA in MR (p = 0.013) and HR (p = 0.023) was observed compared with C, no significant difference in IL-6, TNF-α and CK occurred between groups. We conclude that changes in enzymatic antioxidant defense and inflammatory markers following resistance training are independent of training intensity.
本研究旨在探讨中等强度（MR）和高阻力（HR）训练对全身炎症和循环酶抗氧化活性的影响。30名男性被分为HR组（n = 10）、MR组（n = 10）或对照组（C组；n = 10）。进行了为期八周的阻力训练。在训练前后测量血浆中超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GPX）、肌酸激酶（CK）的活性以及丙二醛（MDA）、白细胞介素-6（IL-6）和肿瘤坏死因子-α（TNF-α）的浓度。结果显示，MR组（p = 0.026）和HR组（p = 0.044）的SOD活性增加。HR组（p = 0.012）和MR组（p = 0.037）的GPX活性显著高于C组。与C组相比，MR组（p = 0.013）和HR组（p = 0.023）的MDA显著降低，而各组之间IL-6、TNF-α和CK无显著差异。我们得出结论，阻力训练后酶抗氧化防御和炎症标志物的变化与训练强度无关。
