Russell C D, Roeher H D, DeLand E C, Maloney J V
Ann Surg. 1978 Apr;187(4):417-22. doi: 10.1097/00000658-197804000-00013.
A method previously established in the experimental animal for predicting the acute response to either metabolic stress (bicarbonate administration) or respiratory stress(manipulation of oxygenator gas during cardiopulmonary bypass) has been extended to man. The method is based on a single nomogram. The accuracy of the nomogram is demonstrated using data from 13 patients on cardiopulmonary bypass. Similar agreement obtains between the nomogram and data reported by others. The nomogram can be used to estimate the therapeutically required dose of bicarbonate.
一种先前在实验动物中建立的用于预测对代谢应激（给予碳酸氢盐）或呼吸应激（体外循环期间对氧合器气体的操作）的急性反应的方法已扩展至人体。该方法基于单个列线图。使用13例体外循环患者的数据证明了列线图的准确性。列线图与其他人报告的数据之间也有类似的一致性。该列线图可用于估计治疗所需的碳酸氢盐剂量。
