Torigoe T, Sato S, Nagayama Y, Sato T, Yamazaki H
Department of Neonatology, Niigata City General Hospital, Niigata, Japan.
Department of Pediatrics, Niigata City General Hospital, Niigata, Japan.
J Perinatol. 2015 Jul;35(7):485-9. doi: 10.1038/jp.2014.245. Epub 2015 Jan 29.
We evaluated electrical velocimetry, a noninvasive method for continuous cardiac output measurement, in very-low and low birth weight infants and the influence of patent ductus arteriosus (PDA) and ventilators on this method.
This prospective study compared 81 pairs of simultaneous cardiac output measurements by electrical velocimetry and transthoracic echocardiography in 28 patients. Data were compared by correlation, Bland-Altman analysis and two-way analysis of variance.
The two methods exhibited a high correlation (r=0.859, P<0.0001). The bias (mean difference of the methods) and percent error (100 × 1.96 × s.d./mean cardiac output) were -6 ml min(-1) and 29.2%, respectively. PDA significantly affected the bias (P=0.0004), but ventilators did not (P=0.14). Hemodynamically significant PDA had a larger bias (-36 ml min(-1)) and higher percent error (38.6%).
Although influenced by PDA, electrical velocimetry was generally interchangeable with transthoracic echocardiography even using ventilators.
我们评估了电测速法，一种用于连续测量心输出量的非侵入性方法，在极低和低出生体重婴儿中的应用，以及动脉导管未闭（PDA）和呼吸机对该方法的影响。
这项前瞻性研究比较了28例患者中通过电测速法和经胸超声心动图同时进行的81对心输出量测量。通过相关性分析、布兰德-奥特曼分析和双向方差分析对数据进行比较。
两种方法显示出高度相关性（r = 0.859，P < 0.0001）。偏差（方法的平均差异）和百分比误差（100×1.96×标准差/平均心输出量）分别为-6 ml min⁻¹和29.2%。PDA显著影响偏差（P = 0.0004），但呼吸机没有（P = 0.14）。血流动力学上显著的PDA偏差更大（-36 ml min⁻¹），百分比误差更高（38.6%）。
尽管受PDA影响，但即使使用呼吸机，电测速法通常也可与经胸超声心动图互换使用。
