Abasolo Lydia, Leon Leticia, Lajas Cristina, Carmona Loreto, Serra Jose Antonio, Reoyo Agustín, Rodriguez-Rodriguez Luis, Jover Juan Ángel
Servicio de Reumatologia, Rheumatology Department, IdISSC, Hospital Clínico San Carlos, Calle Martín Lagos s/n, 28040, Madrid, Spain.
Rheumatol Int. 2015 Jul;35(7):1183-91. doi: 10.1007/s00296-015-3223-3. Epub 2015 Jan 30.
To evaluate the efficacy of a program for subacute physical disability due to musculoskeletal disorders (MSD) in the elderly. We carried out a randomized controlled evaluator-blinded intervention study in a health district (October 2005 to April 2008). Subjects older than 64, starting a subacute MSD episode of physical disability-defined as moderate disability or higher in the Rosser classification-and identified by general practitioners, were randomized into standard care or an early specific program. The program was carried out by rheumatologists following detailed proceedings. Efficacy was defined as the difference between groups in the duration of episodes-time from onset until an improvement larger than a point in the Rosser classification). Hazard ratios (HR) to recovery of the program over standard care were obtained from Cox regression analyses. One hundred and twenty-three patients were included, generating 244 episodes of subacute MSD. Mean duration of episodes was 5 months; 14.5 % of them were chronically disabled throughout follow-up. The program was associated with shorter duration of episodes compared with CG analyzing just the ended ones (p = 0.004). The HR to recovery between groups did not achieve statistical differences. Nevertheless, recovery rate at 12 months and HR from those with moderate physical disability at the inclusion period (Rosser disability level 4, n = 84) were superior in the IG (HR 1.9, p = 0.03; HR 1.93; p = 0.03 respectively). An early intervention program for subacute MSD-related disability in elderly has partial efficacy; the program benefited patients with moderate physical disability and after a year of follow-up.
为评估针对老年人肌肉骨骼疾病(MSD)所致亚急性身体残疾的一项计划的疗效。我们于一个健康区开展了一项随机对照、评估者盲法干预研究(2005年10月至2008年4月)。年龄超过64岁、开始出现亚急性MSD身体残疾发作(在罗瑟分类中定义为中度残疾或更严重残疾)且由全科医生确诊的受试者,被随机分为标准护理组或早期特定计划组。该计划由风湿病学家按照详细程序实施。疗效定义为两组在发作持续时间(从发病至罗瑟分类中改善超过一个等级的时间)上的差异。通过Cox回归分析得出该计划相对于标准护理的恢复风险比(HR)。共纳入123例患者,产生244次亚急性MSD发作。发作的平均持续时间为5个月;其中14.5%在整个随访期间为慢性残疾。仅分析已结束发作的情况时,与对照组相比,该计划与更短的发作持续时间相关(p = 0.004)。两组之间的恢复HR未达到统计学差异。然而,干预组在12个月时的恢复率以及纳入期为中度身体残疾者(罗瑟残疾等级4,n = 84)的HR更高(HR分别为1.9,p = 0.03;HR为1.93;p = 0.03)。针对老年人亚急性MSD相关残疾的早期干预计划具有部分疗效;该计划使中度身体残疾患者受益,且在随访一年后仍有效果。