Wood T J, Moore C S, Saunderson J R, Beavis A W
Radiation Physics Department, Queen's Centre for Oncology and Haematology, Castle Hill Hospital, Hull & East Yorkshire Hospitals NHS Trust, Castle Road, Hull, HU16 5JQ, UK. Department of Engineering, Faculty of Science, University of Hull, Cottingham Road, Hull, HU6 7RX, UK.
J Radiol Prot. 2015 Mar;35(1):153-63. doi: 10.1088/0952-4746/35/1/153. Epub 2015 Jan 30.
The use of cone beam CT in common radiotherapy treatments is increasing with the growth of image guided radiotherapy. Whilst the benefits that this technology offers are clear, such as improved patient positioning prior to treatment, it is always important to consider the implications of such intensive imaging regimes on the patient, especially when considering the fundamental radiation protection requirements for justification and optimisation.The purpose of this study was to develop a technique that uses readily available dose calculation software (PCXMC 2.0) to estimate the organ and effective doses that result from these types of examination in prostate treatments on the Varian OBI system. It has been shown that by separating these types of examinations into 28 different projections, with a range of x-ray beam qualities, it is possible to reproduce the complex geometry that is used on these imaging systems in PCXMC i.e. asymmetric radiation field with a half bowtie filter rotating 360° around the patient.This new technique has been validated with thermo-luminescent dosimeter measurements in the Rando anthropomorphic phantom, and has been shown to give excellent agreement with this established method (R(2) = 0.995). This technique will prove to be valuable to radiotherapy departments that are looking to optimise their CBCT imaging protocols as it allows a rapid evaluation of the impact of any changes on patient dose. It also serves to further highlight the levels of dose that these types of patient are subject to when having daily CBCT scans as part of the treatment, which further reinforces the need for optimisation of both patient dose and image quality on these systems.
随着图像引导放射治疗的发展,锥形束CT在普通放射治疗中的应用日益增加。虽然这项技术带来的益处显而易见,比如在治疗前改善患者定位,但始终有必要考虑这种密集成像方案对患者的影响,尤其是在考虑正当性和优化的基本辐射防护要求时。本研究的目的是开发一种技术,利用现成的剂量计算软件(PCXMC 2.0)来估算在瓦里安OBI系统上进行前列腺治疗时这类检查所产生的器官剂量和有效剂量。研究表明,通过将这类检查分为28种不同的投影,涵盖一系列X射线束质,可以在PCXMC中重现这些成像系统所使用的复杂几何结构,即带有半蝴蝶结滤过器围绕患者旋转360°的不对称辐射野。这项新技术已在兰多人体模型中通过热释光剂量计测量得到验证,并且已证明与这种既定方法具有极佳的一致性(R² = 0.995)。对于希望优化其CBCT成像方案的放射治疗科室而言,这项技术将被证明是有价值的,因为它能够快速评估任何变化对患者剂量的影响。它还进一步凸显了这类患者在作为治疗一部分进行每日CBCT扫描时所接受的剂量水平,这进一步强化了在这些系统上优化患者剂量和图像质量的必要性。