Wood Tim J, Moore Craig S, Horsfield Carl J, Saunderson John R, Beavis Andrew W
1 Radiation Physics Department, Queen's Centre for Oncology and Haematology, Castle Hill Hospital, Hull and East Yorkshire Hospitals NHS Trust, Hull, UK.
2 Faculty of Science, University of Hull, Hull, UK.
Br J Radiol. 2015;88(1055):20150364. doi: 10.1259/bjr.20150364. Epub 2015 Sep 30.
The purpose of this study was to develop size-based radiotherapy kilovoltage cone beam CT (CBCT) protocols for the pelvis.
Image noise was measured in an elliptical phantom of varying size for a range of exposure factors. Based on a previously defined "small pelvis" reference patient and CBCT protocol, appropriate exposure factors for small, medium, large and extra-large patients were derived which approximate the image noise behaviour observed on a Philips CT scanner (Philips Medical Systems, Best, Netherlands) with automatic exposure control (AEC). Selection criteria, based on maximum tube current-time product per rotation selected during the radiotherapy treatment planning scan, were derived based on an audit of patient size.
It has been demonstrated that 110 kVp yields acceptable image noise for reduced patient dose in pelvic CBCT scans of small, medium and large patients, when compared with manufacturer's default settings (125 kVp). Conversely, extra-large patients require increased exposure factors to give acceptable images. 57% of patients in the local population now receive much lower radiation doses, whereas 13% require higher doses (but now yield acceptable images).
The implementation of size-based exposure protocols has significantly reduced radiation dose to the majority of patients with no negative impact on image quality. Increased doses are required on the largest patients to give adequate image quality.
The development of size-based CBCT protocols that use the planning CT scan (with AEC) to determine which protocol is appropriate ensures adequate image quality whilst minimizing patient radiation dose.
本研究旨在制定基于体型的盆腔放射治疗千伏级锥形束CT(CBCT)方案。
在不同尺寸的椭圆形体模中,针对一系列曝光参数测量图像噪声。基于先前定义的“小骨盆”参考患者和CBCT方案,得出适合小、中、大及超大体型患者的曝光参数,这些参数近似于在配备自动曝光控制(AEC)的飞利浦CT扫描仪(飞利浦医疗系统公司,荷兰贝斯特)上观察到的图像噪声表现。根据放疗治疗计划扫描期间所选的每旋转最大管电流-时间乘积,基于对患者体型的审核得出选择标准。
已证明,与制造商的默认设置(125 kVp)相比,在小、中、大体型患者的盆腔CBCT扫描中,110 kVp能在降低患者剂量的情况下产生可接受的图像噪声。相反,超大型患者需要增加曝光参数才能获得可接受的图像。当地人群中57%的患者现在接受的辐射剂量大幅降低,而13%的患者需要更高剂量(但现在能产生可接受的图像)。
基于体型的曝光方案的实施显著降低了大多数患者的辐射剂量,且对图像质量无负面影响。对于体型最大的患者,需要增加剂量以获得足够的图像质量。
基于体型的CBCT方案利用计划CT扫描(配备AEC)来确定合适的方案,既能确保足够的图像质量,又能将患者辐射剂量降至最低。