Tang Li-hong, Shi Le, Yuan Shuang, Lv Jin, Lu Hai-xia
Department of Preventive Dentistry, Shanghai Jing'an Dental Clinic. Shanghai 200042; China.E-mail:
Shanghai Kou Qiang Yi Xue. 2014 Dec;23(6):736-9.
To compare the effectiveness of fluoride vanish, fluoride foam, pit and fissure sealant with fluoride in prevention of dental caries, and investigate appropriate approach to prevent dental caries at schools.
A randomized controlled clinical trial with 4 parallel groups was conducted. Totally 1016 children from 4 schools and 33 classes with a mean age of 7 to 8 years were included. They were randomly allocated into 4 groups: (1) fluoride vanish, semi-annual application; (2) fluoride foam, semi-annual application; (3) resin sealant, single placement; and (4) placebo control with oral hygiene instruction. Follow-up examinations were conducted after 2 years to monitor dental caries increment of first molars among these children. Data analysis was performed using SPSS 18.0 software package.
Two years later, 977 children (96.2%) were examined. The results of multiple factor ANCOVA showed that fluoride vanish and resin sealant had significantly lower mean dental caries increment on tooth surface compared with control group (P<0.05). No significant difference of mean dental caries increment on tooth surface was found between fluoride foam and control group (P>0.05).
The placement of resin sealant with fluoride and annual application of fluoride protector are effective in prevention of dental caries in permanent teeth of children.
比较氟化物涂膜、氟泡沫、窝沟封闭剂与氟化物预防龋齿的效果，并探讨学校预防龋齿的适宜方法。
进行一项有4个平行组的随机对照临床试验。纳入来自4所学校33个班级的1016名儿童，平均年龄7至8岁。他们被随机分为4组：（1）氟化物涂膜，半年应用一次；（2）氟泡沫，半年应用一次；（3）树脂封闭剂，单次应用；（4）安慰剂对照并给予口腔卫生指导。2年后进行随访检查，监测这些儿童第一恒磨牙的龋齿增加情况。使用SPSS 18.0软件包进行数据分析。
2年后，检查了977名儿童（96.2%）。多因素协方差分析结果显示，与对照组相比，氟化物涂膜和树脂封闭剂牙面平均龋齿增加量显著更低（P<0.05）。氟泡沫与对照组之间牙面平均龋齿增加量无显著差异（P>0.05）。
使用含氟树脂封闭剂和每年应用氟保护剂对预防儿童恒牙龋齿有效。
