Varnum Claus, Pedersen Alma B, Kjærsgaard-Andersen Per, Overgaard Søren
Department of Orthopedic Surgery and Traumatology , Odense University Hospital , Odense.
Acta Orthop. 2015;86(4):477-84. doi: 10.3109/17453674.2015.1012975. Epub 2015 Jan 30.
Ceramic-on-ceramic (CoC) bearings were introduced in total hip arthroplasty (THA) to reduce problems related to polyethylene wear. We compared the 9-year revision risk for cementless CoC THA and for cementless metal-on-polyethylene (MoP) THA.
In this prospective, population-based study from the Danish Hip Arthroplasty Registry, we identified all the primary cementless THAs that had been performed from 2002 through 2009 (n = 25,656). Of these, 1,773 THAs with CoC bearings and 9,323 THAs with MoP bearings were included in the study. To estimate the relative risk (RR) of revision, we used regression with the pseudo-value approach and treated death as a competing risk.
444 revisions were identified: 4.0% for CoC THA (71 of 1,773) and 4.0% for MoP THA (373 of 9,323). No statistically significant difference in the risk of revision for any reason was found for CoC and MoP bearings after 9 years of follow-up (adjusted RR = 1.3, 95% CI: 0.72-2.4). Revision rates due to component failure were 0.5% (n = 8) for CoC bearings and 0.1% (n = 6) for MoP bearings (p < 0.001). 6 patients with CoC bearings (0.34%) underwent revision due to ceramic fracture.
When compared to the "standard" MoP bearings, CoC THA had a 33% higher (though not statistically significantly higher) risk of revision for any reason at 9 years.
全髋关节置换术(THA)中引入陶瓷对陶瓷(CoC)关节轴承以减少与聚乙烯磨损相关的问题。我们比较了非骨水泥型CoC全髋关节置换术和非骨水泥型金属对聚乙烯(MoP)全髋关节置换术9年翻修风险。
在这项基于丹麦髋关节置换登记处的前瞻性人群研究中,我们确定了2002年至2009年期间进行的所有初次非骨水泥型全髋关节置换术(n = 25,656)。其中,1773例使用CoC关节轴承的全髋关节置换术和9323例使用MoP关节轴承的全髋关节置换术纳入研究。为了估计翻修的相对风险(RR),我们采用伪值法进行回归分析,并将死亡视为竞争风险。
共确定444例翻修病例:CoC全髋关节置换术为4.0%(1773例中的71例),MoP全髋关节置换术为4.0%(9323例中的373例)。随访9年后,CoC和MoP关节轴承因任何原因的翻修风险无统计学显著差异(调整后RR = 1.3,95% CI:0.72 - 2.4)。因假体失败导致的翻修率,CoC关节轴承为0.5%(n = 8),MoP关节轴承为0.1%(n = 6)(p < 0.001)。6例使用CoC关节轴承的患者(0.34%)因陶瓷骨折接受翻修。
与“标准”MoP关节轴承相比,CoC全髋关节置换术9年时因任何原因的翻修风险高33%(尽管无统计学显著差异)。