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高交联聚乙烯在翻修全髋关节置换术中的高生存率:一项至少10年的随访研究。

High survivorship of highly cross-linked polyethylene in revision Total hip Arthroplasty: a minimum 10-year follow-up study.

作者信息

Lim Seung-Jae, Yeo Ingwon, Park Chan-Woo, Lee Kyung-Jae, Min Byung-Woo, Park Youn-Soo

机构信息

Department of Orthopedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.

Department of Orthopaedic Surgery, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, South Korea.

出版信息

Arthroplasty. 2019 Dec 17;1(1):16. doi: 10.1186/s42836-019-0017-1.

Abstract

PURPOSE

Highly cross-linked polyethylene has been introduced to decrease osteolysis secondary to polyethylene wear debris generation. However, few long-term data on revision total hip arthroplasty (THA) using highly cross-linked polyethylene liners are available. The objective of this study was to determine long-term outcomes of a highly cross-linked polyethylene liner in revision THA.

MATERIALS & METHODS: We evaluated 63 revision THAs performed in 63 patients using a highly cross-linked polyethylene liner between April 2000 and February 2005. Of these, nine died and four were lost to follow-up. Thus, the final study cohort consisted of 50 patients (50 hips), including 26 males and 24 females with a mean age of 53 years (range, 27-75 years). Mean follow-up was 11 years (range, 10-14 years).

RESULTS

The mean Harris hip score improved from 44 points preoperatively to 85 points at the final follow-up. No radiographic evidence of osteolysis was found in any hip. The mean rate of polyethylene liner wear was 0.029 mm/year (range, 0.003 to 0.098 mm/year). A total of 5 hips (10%) required re-revision arthroplasty, including one cup loosening, one recurrent dislocation, and three deep infections. Kaplan-Meier survivorship with an end point of re-revision for any reason was 91.1% and for aseptic cup loosening was 97.9% at 11 years.

CONCLUSION

At a minimum of 10 years, the highly cross-linked polyethylene liners showed excellent clinical performance and implant survivorship, and were not associated with osteolysis in our patients with revision THAs.

摘要

目的

高交联聚乙烯已被引入以减少因聚乙烯磨损碎屑产生而导致的骨溶解。然而,关于使用高交联聚乙烯衬垫进行翻修全髋关节置换术(THA)的长期数据很少。本研究的目的是确定高交联聚乙烯衬垫在翻修THA中的长期疗效。

材料与方法

我们评估了2000年4月至2005年2月期间63例患者使用高交联聚乙烯衬垫进行的63例翻修THA。其中,9例死亡,4例失访。因此,最终研究队列包括50例患者(50髋),其中男性26例,女性24例,平均年龄53岁(范围27 - 75岁)。平均随访时间为11年(范围10 - 14年)。

结果

Harris髋关节评分平均从术前的44分提高到末次随访时的85分。任何髋关节均未发现骨溶解的影像学证据。聚乙烯衬垫的平均磨损率为0.029毫米/年(范围0.003至0.098毫米/年)。共有5髋(10%)需要再次翻修关节置换术,包括1例髋臼松动、1例复发性脱位和3例深部感染。以任何原因再次翻修为终点的Kaplan - Meier生存率在11年时为91.1%,无菌性髋臼松动的生存率为97.9%。

结论

至少10年时,高交联聚乙烯衬垫在我们的翻修THA患者中显示出优异的临床性能和植入物生存率,且与骨溶解无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa0a/8796417/75f1ad254132/42836_2019_17_Fig1_HTML.jpg

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