Cervantes Arriaga Amin, Rodríguez Violante Mayela, Camacho Ordóñez Azyadeh, González Latapi Paulina, López Ruiz Minerva, Estrada Bellmann Ingrid, Zúñiga Ramírez Carlos, Otero Cerdeira Elisa
Instituto Nacional de Neurología y Neurocirugía, México, D.F.
Hospital General de México, México, D.F.
Gac Med Mex. 2014 Dec;150 Suppl 2:242-7.
Parkinson's disease is characterized by a wide spectrum of motor and non-motor symptoms with an insidious onset. Identification of these symptoms by the patient as well as by the physician is determinant in order to achieve an early diagnosis.
To determine the time from motor symptoms onset to the diagnosis of Parkinson's disease and analyze the clinical and demographic factors related to it.
A cross-sectional study was carried out including subjects with Parkinson's disease seen during the 2011-2012 period and belonging to the Mexican National Parkinson's Registry. Time from symptom onset to the diagnosis was collected; its relation with demographic and clinical characteristics was assessed.
A total of 1,062 subjects were included. Delay in diagnosis was 29.5 months. Predictive factors for a longer diagnostic delay were symptoms onset before 40 years of age (B: -0.350; p < 0.001) and a positive family history of Parkinson's disease (B: 0.224; p < 0.001).
The diagnosis of Parkinson´s disease in Mexico is two and a half times greater than what has been reported for other countries.
帕金森病的特点是起病隐匿，伴有广泛的运动和非运动症状。患者及医生对这些症状的识别对于早期诊断至关重要。
确定从运动症状出现到帕金森病诊断的时间，并分析与之相关的临床和人口统计学因素。
进行了一项横断面研究，纳入2011 - 2012年期间就诊于墨西哥国家帕金森病登记处的帕金森病患者。收集从症状出现到诊断的时间；评估其与人口统计学和临床特征的关系。
共纳入1062名受试者。诊断延迟为29.5个月。诊断延迟较长的预测因素为40岁之前出现症状（B：-0.350；p < 0.001）和帕金森病家族史阳性（B：0.224；p < 0.001）。
墨西哥帕金森病的诊断时间比其他国家报道的长两倍半。
