Alwan Iqdam Abdulmaged, Awadh Ammar Ihsan, Tangiisuran Balamurugan, Khan Halilol Rahman Mohamed, Yahaya Noorfatimah, Majid Mohamed Isa
Integrative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Penang, Malaysia.
Department of Pharmacy, Al-Kunooze University College, Basra, Iraq.
J Pharm Bioallied Sci. 2020 Oct-Dec;12(4):475-481. doi: 10.4103/jpbs.JPBS_340_19. Epub 2020 Oct 8.
The wide availability of medications has led to an increased exposure of humans to the possibility of poisoning. An unavoidable effect due to the availability of these medications has also led to a rising increment in the number of poisoning cases. All drugs, especially when administered in large doses or overextended periods, can initiate a toxic condition. Therefore, the objective of this study was to examine nationwide, the patterns attributed to poisoning, and to describe the sociodemographic, and geographic distribution of poisoning, by identifying the category of substances implicated in these cases.
A retrospective study based on telephone calls reported on poisoning caused by pharmaceutical products undertaken by the National Poisoning Centre (NPC) in Penang (Malaysia) was used as the basis of this study covering the period between 2010 and 2015. The study included the mode and type of poisoning, exposure routes as well as the incidence locations.
A total of 10,998 cases were examined, finding that females represented 5,899 cases (53.6%) being intoxicated more frequently compared to the number of males, 3,839 (34.9%). The age group of poisoning cases ranged between 20 and 29 years representing 2,579 (23.4%) of reported cases. The common mode of poisoning was attributed to suicide 5,203 (47.3%) from among the 10,998 cases and the highest poisoning agents reported were from the psychiatric group of pharmaceutical products of 2,287 (21%).
These findings indicate a rising trend of suicidal poisoning attempts between 2013 and 2015, which emphasizes the need for more stringent and effective enforcement protocols to limit the rising incidence of poisoning. As such, analyzing the trends in poisoning in a particular zone periodically could help health policy-makers to develop management policies and prevention strategies.
药物的广泛可得性导致人类接触中毒可能性增加。这些药物的可得性所带来的一个不可避免的影响是中毒病例数量不断上升。所有药物,尤其是大剂量或长期服用时,都可能引发中毒状况。因此,本研究的目的是在全国范围内检查中毒模式,并通过确定这些病例中涉及的物质类别来描述中毒的社会人口统计学和地理分布。
本研究以马来西亚槟城国家中毒中心(NPC)报告的药品中毒电话记录为基础,进行回顾性研究,涵盖2010年至2015年期间。该研究包括中毒的方式和类型、接触途径以及发生地点。
共检查了10998例病例,发现女性有5899例(53.6%)中毒,比男性的3839例(34.9%)更频繁。中毒病例的年龄组在20至29岁之间,占报告病例的2579例(23.4%)。中毒的常见方式是自杀,在10998例病例中有5203例(47.3%),报告的中毒药物中最多的是精神类药品,有2287例(21%)。
这些发现表明2013年至2015年期间自杀性中毒企图呈上升趋势,这强调需要更严格有效的执法方案来限制中毒发生率的上升。因此,定期分析特定区域的中毒趋势有助于卫生政策制定者制定管理政策和预防策略。