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本文引用的文献

1
Endoscopic hydroxyapatite augmentation for patulous Eustachian tube.经内镜羟基磷灰石填充治疗咽鼓管异常开放
Laryngoscope. 2014 Jan;124(1):62-6. doi: 10.1002/lary.24250. Epub 2013 Jul 29.
2
Endoscopic ligation of the patulous eustachian tube as treatment for autophony.内镜下扩张的咽鼓管结扎术治疗自声。
Laryngoscope. 2013 Jan;123(1):239-43. doi: 10.1002/lary.23635. Epub 2012 Oct 15.
3
Management of patulous eustachian tube with habitual sniffing.习惯性擤鼻导致咽鼓管异常开放的处理。
Otol Neurotol. 2011 Jul;32(5):790-3. doi: 10.1097/MAO.0b013e3182184e23.
4
Autologous cartilage injection for the patulous eustachian tube.自体软骨注射治疗咽鼓管扩张。
Am J Otolaryngol. 2011 Jul-Aug;32(4):346-8. doi: 10.1016/j.amjoto.2010.03.008. Epub 2010 May 14.
5
Diagnosis and management of the patulous eustachian tube.咽鼓管异常开放的诊断与处理
Otol Neurotol. 2007 Aug;28(5):668-77. doi: 10.1097/mao.0b013e31804d4998.
6
Ligation of eustachian tube for intractable patulous eustachian tube: a preliminary report.咽鼓管结扎术治疗难治性咽鼓管异常开放症:初步报告
Eur Arch Otorhinolaryngol. 2007 Apr;264(4):353-7. doi: 10.1007/s00405-006-0185-9. Epub 2006 Oct 24.
7
Trans-tympanic silicone plug insertion for chronic patulous Eustachian tube.经鼓膜插入硅胶塞治疗慢性咽鼓管异常开放
Acta Otolaryngol. 2005 Nov;125(11):1158-63. doi: 10.1080/00016480510038167.
8
ABNORMAL PATENCY OF THE EUSTACHIAN TUBE: REPORT ON 41 CASES.咽鼓管异常通畅:41例报告。
Laryngoscope. 1964 Feb;74:267-71. doi: 10.1002/lary.5540740211.
9
Autologous fat grafting for the refractory patulous eustachian tube.自体脂肪移植治疗难治性咽鼓管异常开放症
Otolaryngol Head Neck Surg. 2003 Jan;128(1):88-91. doi: 10.1067/mhn.2003.34.
10
"How I do it"--otology and neurotology. A specific issue and its solution. Management of the patulous Eustachian tube.“我的做法”——耳科学与神经耳科学。一个特定问题及其解决方案。咽鼓管异常开放的处理
Laryngoscope. 1981 Jan;91(1):149-52. doi: 10.1288/00005537-198101000-00023.

咽鼓管异常开放的外科治疗:一项系统评价

Surgical management of Patulous Eustachian tube: A systematic review.

作者信息

Hussein Ahmed A, Adams Austin S, Turner Justin H

机构信息

Department of Otolaryngology-Head and Neck Surgery, Cairo University School of Medicine, Cairo, Egypt.

Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, U.S.A.

出版信息

Laryngoscope. 2015 Sep;125(9):2193-8. doi: 10.1002/lary.25168. Epub 2015 Feb 3.

DOI:10.1002/lary.25168
PMID:25646902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4725712/
Abstract

OBJECTIVES

Patulous Eustachian tube (PET) is a challenging clinical problem with limited medical and surgical options. The current study systematically reviews the literature to determine the safety and efficacy of surgical treatments for PET.

DATA SOURCES

Medline, Google Scholar, and Cochrane databases.

METHODS

Studies evaluating the surgical management of PET were extracted based on defined inclusion criteria. Data including surgical techniques, outcomes, and complications were extracted and analyzed.

RESULTS

A total of 1,616 studies were retrieved from the initial search. Of these, 14 studies comprising a total of 226 patients (253 sides) met inclusion criteria and were evaluated for surgical techniques, patient outcomes, and complications. As defined by the Oxford Center for Evidence-Based Medicine (Oxford, UK), all studies were classified as level 4 evidence. The most commonly reported techniques were ET plugging (3 studies), PE tube placement (2 studies), and suture ligation (2 studies). Postoperative follow-up ranged from 2 to 60 months (mean, 20.6 months). Outcome measures varied significantly between individual studies, with overall symptom improvement reported between 22% and 100% (mean 72.4%; 95% CI, 62.5%-81.2%). A low incidence of minor complications was reported in nine of 14 studies.

CONCLUSIONS

Current literature evaluating the surgical management of PET is limited and comprised entirely of level 4 studies. Comparisons between techniques were not possible due to the small number of studies and variable outcome measures. Future larger studies evaluating defined outcomes and quality-of-life measures are needed to determine the comparative efficacy of surgical treatments for this challenging condition.

摘要

目的

咽鼓管异常开放(PET)是一个具有挑战性的临床问题,药物和手术治疗选择有限。本研究系统回顾文献,以确定PET手术治疗的安全性和有效性。

数据来源

医学文献数据库、谷歌学术和考克兰数据库。

方法

根据既定的纳入标准提取评估PET手术治疗的研究。提取并分析包括手术技术、结果和并发症在内的数据。

结果

初步检索共获得1616项研究。其中,14项研究共纳入226例患者(253侧),符合纳入标准,并对手术技术、患者结果和并发症进行了评估。根据英国牛津循证医学中心的定义,所有研究均归类为4级证据。最常报道的技术是咽鼓管堵塞(3项研究)、咽鼓管置管(2项研究)和缝合结扎(2项研究)。术后随访时间为2至60个月(平均20.6个月)。各研究之间的结果测量差异很大,总体症状改善率在22%至100%之间(平均72.4%;95%CI,62.5%-81.2%)。14项研究中有9项报道了轻微并发症的发生率较低。

结论

目前评估PET手术治疗的文献有限,且完全由4级研究组成。由于研究数量少和结果测量方法多样,无法对不同技术进行比较。未来需要开展更大规模的研究,评估明确的结果和生活质量指标,以确定针对这一具有挑战性病症的手术治疗的相对疗效。