Federau Christian, O'Brien Kieran, Birbaumer Adrien, Meuli Reto, Hagmann Patric, Maeder Philippe
Department of Diagnostic and Interventional Radiology, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne, Lausanne, Switzerland.
Center for Biomedical Imaging (CIBM), University of Geneva, Geneva, Switzerland.
PLoS One. 2015 Feb 3;10(2):e0117706. doi: 10.1371/journal.pone.0117706. eCollection 2015.
Functional imaging with intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) is demonstrated. Images were acquired at 3 Tesla using a standard Stejskal-Tanner diffusion-weighted echo-planar imaging sequence with multiple b-values. Cerebro-spinal fluid signal, which is highly incoherent, was suppressed with an inversion recovery preparation pulse. IVIM microvascular perfusion parameters were calculated according to a two-compartment (vascular and non-vascular) diffusion model. The results obtained in 8 healthy human volunteers during visual stimulation are presented. The IVIM blood flow related parameter fD* increased 170% during stimulation in the visual cortex, and 70% in the underlying white matter.
展示了体素内不相干运动（IVIM）磁共振成像（MRI）的功能成像。使用具有多个b值的标准Stejskal-Tanner扩散加权回波平面成像序列在3特斯拉下采集图像。通过反转恢复准备脉冲抑制高度不相干的脑脊液信号。根据双室（血管和非血管）扩散模型计算IVIM微血管灌注参数。呈现了8名健康人类志愿者在视觉刺激期间获得的结果。在视觉刺激期间，视觉皮层中与IVIM血流相关的参数fD*增加了170%，其下方白质中增加了70%。
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