Ohashi Hiroyuki, Hasegawa Mai, Wakimoto Kentaro, Miyamoto-Sato Etsuko
Division of Interactome Medical Sciences, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.
Division of Interactome Medical Sciences, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan ; Division of Molecular Biology, Tokyo University of Science Research Institute for Biomedical Science, 2669 Yamazaki, Noda, Chiba 278-0022, Japan.
Biomed Res Int. 2015;2015:104209. doi: 10.1155/2015/104209. Epub 2015 Jan 12.
The development of high-speed analytical techniques such as next-generation sequencing and microarrays allows high-throughput analysis of biological information at a low cost. These techniques contribute to medical and bioscience advancements and provide new avenues for scientific research. Here, we outline a variety of new innovative techniques and discuss their use in omics research (e.g., genomics, transcriptomics, metabolomics, proteomics, and interactomics). We also discuss the possible applications of these methods, including an interactome sequencing technology that we developed, in future medical and life science research.
诸如新一代测序和微阵列等高速分析技术的发展，使得能够以低成本对生物信息进行高通量分析。这些技术推动了医学和生物科学的进步，并为科学研究提供了新途径。在此，我们概述了各种新型创新技术，并讨论了它们在组学研究（如基因组学、转录组学、代谢组学、蛋白质组学和相互作用组学）中的应用。我们还讨论了这些方法，包括我们开发的一种相互作用组测序技术，在未来医学和生命科学研究中的可能应用。
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