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Oral implications of polypharmacy in the elderly.老年人多重用药的口腔影响。
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2
Effect of amifostine in head and neck cancer patients treated with radiotherapy: a systematic review and meta-analysis based on randomized controlled trials.氨磷汀在接受放疗的头颈癌患者中的作用:基于随机对照试验的系统评价和荟萃分析
PLoS One. 2014 May 2;9(5):e95968. doi: 10.1371/journal.pone.0095968. eCollection 2014.
3
The efficacy of a topical sialogogue spray containing 1% malic acid in patients with antidepressant-induced dry mouth: a double-blind, randomized clinical trial.一种含有 1%苹果酸的局部唾液分泌促进剂喷雾在抗抑郁药引起的口干患者中的疗效:一项双盲、随机临床试验。
Depress Anxiety. 2013 Feb;30(2):137-42. doi: 10.1002/da.22017. Epub 2012 Nov 1.
4
Effectiveness of malic acid 1% in patients with xerostomia induced by antihypertensive drugs.1%苹果酸治疗抗高血压药引起的口干症的疗效。
Med Oral Patol Oral Cir Bucal. 2013 Jan 1;18(1):e49-55. doi: 10.4317/medoral.18206.
5
A systematic review of methods to diagnose oral dryness and salivary gland function.口腔干燥和唾液腺功能诊断方法的系统评价。
BMC Oral Health. 2012 Aug 8;12:29. doi: 10.1186/1472-6831-12-29.
6
Xerostomia and salivary hypofunction in vulnerable elders: prevalence and etiology.口干症和脆弱老年人唾液分泌减少:患病率和病因。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Jul;114(1):52-60. doi: 10.1016/j.oooo.2011.11.014. Epub 2012 May 4.
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Intraoral electrostimulator for xerostomia relief: a long-term, multicenter, open-label, uncontrolled, clinical trial.用于口干缓解的口腔内电刺激器:一项长期、多中心、开放性、非对照、临床研究。
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Oral health of psychiatric patients: the nurse's perspective.精神科患者的口腔健康:护士的视角。
Int J Dent Hyg. 2012 Nov;10(4):245-9. doi: 10.1111/j.1601-5037.2011.00537.x. Epub 2011 Dec 22.
9
Interventions for the management of dry mouth: topical therapies.口干管理的干预措施:局部治疗
Cochrane Database Syst Rev. 2011 Dec 7(12):CD008934. doi: 10.1002/14651858.CD008934.pub2.
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Dental patients' self-reports of xerostomia and associated risk factors.口腔干燥症患者的自我报告及相关危险因素。
J Am Dent Assoc. 2011 Jul;142(7):811-6. doi: 10.14219/jada.archive.2011.0269.

口干症和唾液分泌减少的诊断和治疗。

Diagnosis and management of xerostomia and hyposalivation.

机构信息

Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA, USA ; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA.

Department of General Dentistry, Boston University Henry M Goldman School of Dental Medicine, Boston, MA, USA.

出版信息

Ther Clin Risk Manag. 2014 Dec 22;11:45-51. doi: 10.2147/TCRM.S76282. eCollection 2015.

DOI:10.2147/TCRM.S76282
PMID:25653532
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4278738/
Abstract

Xerostomia, the subjective complaint of dry mouth, and hyposalivation remain a significant burden for many individuals. Diagnosis of xerostomia and salivary gland hypofunction is dependent upon a careful and detailed history and thorough oral examination. There exist many options for treatment and symptom management: salivary stimulants, topical agents, saliva substitutes, and systemic sialogogues. The aim of this review is to investigate the current state of knowledge on management and treatment of patients affected by xerostomia and/or hyposalivation.

摘要

口干,即主观感觉到的口腔干燥,以及唾液分泌减少,仍然给许多人带来了严重的负担。口干和唾液腺功能低下的诊断取决于仔细而详细的病史和全面的口腔检查。有许多治疗和症状管理选择:唾液刺激剂、局部制剂、唾液替代品和全身唾液分泌剂。本综述旨在研究目前关于口干和/或唾液分泌减少患者的管理和治疗的知识现状。