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简单评分系统在预测弥漫性腹膜炎发病率和死亡率中的预后意义

Prognostic Significance of Simple Scoring Systems in the Prediction of Diffuse Peritonitis Morbidity and Mortality.

作者信息

Špička Petr, Chudáček Josef, Řezáč Tomáš, Starý Lubomír, Horáček Rostislav, Klos Dušan

机构信息

First Department of Surgery, University Hospital Olomouc, 779 00 Olomouc, Czech Republic.

Department of Anesthesiology, Resuscitation and Intensive Care, University Hospital Olomouc, 779 00 Olomouc, Czech Republic.

出版信息

Life (Basel). 2022 Mar 28;12(4):487. doi: 10.3390/life12040487.

Abstract

INTRODUCTION

Diffuse peritonitis is a serious disease. It is often addressed within urgent management of an unstable patient in shock. The therapy consists of treatment of the source of peritonitis, decontamination of the abdominal cavity, stabilization of the patient and comprehensive resuscitation care in an intensive care unit. A number of scoring systems to determine patient prognosis are available, but most of them require complex input data, making their practical application a substantial problem.

OBJECTIVE

Our aim was to assess simple scoring systems within a cohort, evaluate the level of mortality, morbidity, and duration of hospital stay, followed by a comparison of the acquired data with the literature and determination of an easily implementable scoring system for use in clinical practice.

MATERIAL AND METHODS

We evaluated a group of patients with diffuse peritonitis who underwent surgery in the 2015-2019 period. Medical history, surgical findings, and paraclinical examinations were used as the input for four scoring systems commonly used in practice-MPI, qSOFA, ECOG, and ASA. We compared the results between the systems and with the literature.

RESULTS

Our cohort included 274 patients diagnosed with diffuse peritonitis. Mortality was 22.6%, morbidity 73.4%, with a 25.2 day average duration of hospital stay. Mortality and morbidity increased with rising MPI and qSOFA, well-established scoring systems, but also with rising ASA and ECOG, similarly to MPI and qSOFA.

CONCLUSIONS

The utilized scoring systems correlated well with the severity of the condition and with predicted mortality and morbidity as reported in the literature. Simple scoring systems primarily used in other indications (i.e., ASA and ECOG) have a similar predictive value in our cohort as commonly used systems (MPI, qSOFA). We recommend them in routine clinical practice due to their simplicity.

摘要

引言

弥漫性腹膜炎是一种严重疾病。通常在对休克状态下不稳定患者进行紧急处理时予以应对。治疗包括腹膜炎源头治疗、腹腔去污、患者稳定以及在重症监护病房进行全面复苏护理。有多种用于确定患者预后的评分系统,但其中大多数需要复杂的输入数据,这使得它们的实际应用成为一个重大问题。

目的

我们的目的是在一个队列中评估简单评分系统,评估死亡率、发病率和住院时间,然后将获得的数据与文献进行比较,并确定一种易于在临床实践中实施的评分系统。

材料与方法

我们评估了一组在2015年至2019年期间接受手术的弥漫性腹膜炎患者。病史、手术发现和辅助检查被用作实践中常用的四种评分系统——MPI、qSOFA、ECOG和ASA的输入数据。我们比较了这些系统之间的结果以及与文献的结果。

结果

我们的队列包括274例被诊断为弥漫性腹膜炎的患者。死亡率为22.6%,发病率为73.4%,平均住院时间为25.2天。死亡率和发病率随着MPI和qSOFA(成熟的评分系统)的升高而增加,但也随着ASA和ECOG的升高而增加,与MPI和qSOFA情况类似。

结论

所使用的评分系统与病情严重程度以及文献报道的预测死亡率和发病率密切相关。主要用于其他适应症的简单评分系统(即ASA和ECOG)在我们的队列中与常用系统(MPI、qSOFA)具有相似的预测价值。由于其简单性,我们在常规临床实践中推荐使用它们。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3175/9028034/45096b81d4f9/life-12-00487-g001.jpg

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