Semeijn E J, Korten N C M, Comijs H C, Michielsen M, Deeg D J H, Beekman A T F, Kooij J J S
Department of Psychiatry,The Netherlands EMGO Institute for Health and Care Research,VU University Medical Center,Amsterdam,the Netherlands.
Department of Epidemiology and Biostatistics,VU University Medical Center,Amsterdam,the Netherlands.
Int Psychogeriatr. 2015 Sep;27(9):1467-76. doi: 10.1017/S1041610215000010. Epub 2015 Feb 6.
Research illustrates cognitive deficits in children and younger adults with attention-deficit/hyperactivity disorder (ADHD). Few studies have focused on the cognitive functioning in older adults. This study investigates the association between ADHD and cognitive functioning in older adults.
Data were collected in a cross-sectional side study of the Longitudinal Aging Study Amsterdam (LASA). A diagnostic interview to diagnose ADHD was administered among a subsample (N = 231, age 60-94). ADHD symptoms and diagnosis were assessed with the Diagnostic Interview for ADHD in Adults (DIVA) 2.0. Cognitive functioning was assessed with tests in the domains of executive functioning, information processing speed, memory, and attention/working memory.
Regression analyses indicate that ADHD diagnosis and ADHD severity were only negatively associated with cognitive functioning in the attention/working memory domain. When adjusting for depression, these associations were no longer significant.
The study shows that ADHD in older adults is associated with lower cognitive functioning in the attention/working memory domain. However, this was partly explained by depressive symptoms.
研究表明，患有注意力缺陷多动障碍（ADHD）的儿童和年轻人存在认知缺陷。很少有研究关注老年人的认知功能。本研究调查了老年人ADHD与认知功能之间的关联。
数据收集于阿姆斯特丹纵向衰老研究（LASA）的一项横断面辅助研究。对一个子样本（N = 231，年龄60 - 94岁）进行了ADHD诊断访谈。使用成人ADHD诊断访谈（DIVA）2.0评估ADHD症状和诊断。通过执行功能、信息处理速度、记忆以及注意力/工作记忆等领域的测试评估认知功能。
回归分析表明，ADHD诊断和ADHD严重程度仅与注意力/工作记忆领域的认知功能呈负相关。在调整抑郁因素后，这些关联不再显著。
该研究表明，老年人的ADHD与注意力/工作记忆领域较低的认知功能相关。然而，这部分可由抑郁症状来解释。
