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一只年轻的印度恒河猴(猕猴属)出现类科茨病视网膜病变。

Coats-like retinopathy in a Young Indian Rhesus Macaque (Macaca mulatta).

作者信息

Liu David X, Gilbert Margaret H, Wang Xiaolei, Didier Peter J, Shields Carol L, Lackner Andrew A

机构信息

The Divisions of Comparative Pathology, Tulane University, Covington, LA, USA.

出版信息

J Med Primatol. 2015 Apr;44(2):108-12. doi: 10.1111/jmp.12166. Epub 2015 Feb 6.

Abstract

A 1-year-old male Indian rhesus macaque presented with a bilateral blindness. Ocular examination, gross and histopathological evaluation, and immunohistochemistry were performed. The major findings were retinal telangiectasia, accumulation of exudate in the intraretinal and subretinal space, and retinal detachment. Coat-like retinopathy was diagnosed, and it has not been previously reported in veterinary medicine.

摘要

一只1岁的雄性印度恒河猴出现双侧失明。进行了眼部检查、大体和组织病理学评估以及免疫组织化学检查。主要发现为视网膜毛细血管扩张、视网膜内和视网膜下间隙有渗出物积聚以及视网膜脱离。诊断为外层渗出性视网膜病变,此前在兽医学中尚未有过报道。

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本文引用的文献

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Intravitreal bevacizumab for pediatric exudative retinal diseases.玻璃体内注射贝伐单抗治疗儿童渗出性视网膜疾病。
Saudi J Ophthalmol. 2011 Apr;25(2):193-7. doi: 10.1016/j.sjopt.2011.01.012. Epub 2011 Jan 31.
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Coats disease and exudative retinopathy.科茨病与渗出性视网膜病变。
Int Ophthalmol Clin. 2011 Winter;51(1):93-112. doi: 10.1097/IIO.0b013e318200de51.
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Retinitis pigmentosa.视网膜色素变性
Lancet. 2006 Nov 18;368(9549):1795-809. doi: 10.1016/S0140-6736(06)69740-7.
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Immunopathologic features of inflammatory coats disease.炎症性外层疾病的免疫病理特征。
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