文献检索，用中文搜 PubMed

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Lindström-Seppä P, Vuorinen P J, Vuorinen M, Hänninen O

University of Kuopio, Department of Physiology, Finland.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1989;92(1):51-4. doi: 10.1016/0742-8413(89)90201-6.

The effect of bleached kraft pulp mill effluent (BKME) on xenobiotic biotransformation enzyme activities in the liver of vendace (Coregonus albula L.) was studied by exposing some fish in field laboratory tanks at 0, 0.1, 0.2 and 0.5% (v/v) effluent concentrations of BKME corresponding to 0-0.08 toxic units and others in clean water as controls. 2. Slight increase (57%, 68%) in polysubstrate monooxygenase enzyme activities, measured as benzo(a)pyrene hydroxylase and 7-ethoxycoumarin O-deethylase activities, was observed in a dose related manner after 70 days of exposure to 0.5% concentration of BKME. 3. Highest increase was observed at 0.2% effluent concentration after 120 days of exposure, measured as benzo(a)pyrene hydroxylase activity. 4. BKME had an affect on UDPglucuronosyltransferase, at the beginning (14-70 days) by decreasing and in longer exposure (120 days) by slightly increasing the activity.

通过将一些白鲑（Coregonus albula L.）置于现场实验室水箱中，分别暴露于浓度为0、0.1%、0.2%和0.5%（v/v）的漂白硫酸盐制浆厂废水（BKME）中（对应0 - 0.08个毒性单位），另一些置于清水中作为对照，研究了BKME对其肝脏中异生物质生物转化酶活性的影响。2. 在暴露于0.5%浓度的BKME 70天后，以苯并(a)芘羟化酶和7 - 乙氧基香豆素O - 脱乙基酶活性衡量的多底物单加氧酶活性呈剂量相关方式略有增加（分别增加57%、68%）。3. 在暴露120天后，以苯并(a)芘羟化酶活性衡量，在废水浓度为0.2%时观察到最高增幅。4. BKME对尿苷二磷酸葡萄糖醛酸基转移酶有影响，开始时（14 - 70天）活性降低，长时间暴露（120天）时活性略有增加。

Lindström-Seppä P, Vuorinen P J, Vuorinen M, Hänninen O

University of Kuopio, Department of Physiology, Finland.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1989;92(1):51-4. doi: 10.1016/0742-8413(89)90201-6.

The effect of bleached kraft pulp mill effluent (BKME) on xenobiotic biotransformation enzyme activities in the liver of vendace (Coregonus albula L.) was studied by exposing some fish in field laboratory tanks at 0, 0.1, 0.2 and 0.5% (v/v) effluent concentrations of BKME corresponding to 0-0.08 toxic units and others in clean water as controls. 2. Slight increase (57%, 68%) in polysubstrate monooxygenase enzyme activities, measured as benzo(a)pyrene hydroxylase and 7-ethoxycoumarin O-deethylase activities, was observed in a dose related manner after 70 days of exposure to 0.5% concentration of BKME. 3. Highest increase was observed at 0.2% effluent concentration after 120 days of exposure, measured as benzo(a)pyrene hydroxylase activity. 4. BKME had an affect on UDPglucuronosyltransferase, at the beginning (14-70 days) by decreasing and in longer exposure (120 days) by slightly increasing the activity.

通过将一些白鲑（Coregonus albula L.）置于现场实验室水箱中，分别暴露于浓度为0、0.1%、0.2%和0.5%（v/v）的漂白硫酸盐制浆厂废水（BKME）中（对应0 - 0.08个毒性单位），另一些置于清水中作为对照，研究了BKME对其肝脏中异生物质生物转化酶活性的影响。2. 在暴露于0.5%浓度的BKME 70天后，以苯并(a)芘羟化酶和7 - 乙氧基香豆素O - 脱乙基酶活性衡量的多底物单加氧酶活性呈剂量相关方式略有增加（分别增加57%、68%）。3. 在暴露120天后，以苯并(a)芘羟化酶活性衡量，在废水浓度为0.2%时观察到最高增幅。4. BKME对尿苷二磷酸葡萄糖醛酸基转移酶有影响，开始时（14 - 70天）活性降低，长时间暴露（120天）时活性略有增加。