Anyanechi C E, Saheeb B D
Department of Dental Surgery, University of Calabar Teaching Hospital, Calabar, Nigeria.
Niger J Clin Pract. 2015 Mar-Apr;18(2):251-5. doi: 10.4103/1119-3077.151054.
There is a paucity of literature on the use of honey in wound healing after oral and maxillofacial surgical procedures.
To evaluate the efficacy of the healing properties of Obudu honey in patients who developed wound dehiscence after segmental mandibular resections.
This was a prospective study of 72 patients who had benign lesions of the mandible, and were treated by segmental mandibular resection, with the surgical wounds developing dehiscence. The subjects were randomized into two treatment groups of A (control, n = 36) and B (experimental, n = 36). Unlike the control, the wounds in the experimental group were dressed in honey after debridement.
The ages of the patients ranged from 21 to 73 years with a mean age of 46.3 ± 2.1 years while the male: female ratio was 3:1. There was no significant demographic difference about age ( P = 0.44) and gender (P = 0.38) between the two groups. The smaller the initial circumference of the surgical wound, the shorter the duration of healing and this was significant (P = 0.001) in either of the treatment groups. Numerically, more healing was completed in the first 5 weeks in subjects in the experimental group (n = 19, 52.8%) than the control (n = 13, 36.1%). However, the duration of healing between the subjects in the control and experimental groups at the end of 9 weeks showed no significant difference (P = 0.23).
Honey speeds up the healing of dehiscence wounds of resected mandible when used as dressing more than the control.
关于蜂蜜在口腔颌面外科手术后伤口愈合中的应用，相关文献较少。
评估奥布杜蜂蜜对下颌骨节段性切除术后伤口裂开患者的愈合效果。
这是一项前瞻性研究，纳入72例下颌骨良性病变患者，均接受下颌骨节段性切除术，术后手术伤口出现裂开。将受试者随机分为两组，A组（对照组，n = 36）和B组（试验组，n = 36）。与对照组不同，试验组伤口在清创后用蜂蜜换药。
患者年龄在21至73岁之间，平均年龄为46.3±2.1岁，男女比例为3:1。两组在年龄（P = 0.44）和性别（P = 0.38）方面无显著人口统计学差异。手术伤口初始周长越小，愈合时间越短，在任何一个治疗组中这一差异均有统计学意义（P = 0.001）。从数值上看，试验组在前5周完成愈合的受试者（n = 19，52.8%）多于对照组（n = 13，36.1%）。然而，对照组和试验组受试者在9周结束时的愈合时间无显著差异（P = 0.23）。
与对照组相比，蜂蜜作为敷料用于下颌骨切除术后裂开伤口时，能加速伤口愈合。
