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蜂蜜在手术伤口上的局部应用:一项随机临床试验。

Topical Application of Honey on Surgical Wounds: A Randomized Clinical Trial.

作者信息

Goharshenasan Peiman, Amini Shahideh, Atria Ali, Abtahi Hamidreza, Khorasani Ghasemali

机构信息

Plastic and Reconstructive Surgery Division, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Forsch Komplementmed. 2016;23(1):12-5. doi: 10.1159/000441994. Epub 2016 Feb 9.

DOI:10.1159/000441994
PMID:26977860
Abstract

BACKGROUND

The antimicrobial and anti-inflammatory activity of honey and its ability to accelerate wound healing make it an attractive option in surgical wound care. We performed a randomized clinical trial to compare the efficacy of honey dressing with conventional dressing regarding the aesthetic outcome.

PATIENTS AND METHODS

Bilateral symmetric incisions in randomly selected plastic surgical patients were randomly covered postoperatively with conventional dressing and honey dressing for five days. The aesthetic outcome of the two sides was rated on a Visual Analog Scale by the surgeon and the patient and compared at month three and six after surgery.

RESULTS

Seventy two symmetrical incisions in 52 patients were evaluated during the study. The mean width of the scar after the third and the sixth month was 3.64 +/- 0.83 mm and 3.49 +/- 0.87 mm on the side that received honey dressing and 5.43 +/- 0.05 mm and 5.30+/- 1.35 mm in the control group. Wilcoxon signed-rank test showed significant difference between honey and conventional dressing outcomes at third and sixth month (p < 0.001).

CONCLUSION

The healing process of the surgical wound and its final aesthetic result could be improved by using honey dressing.

摘要

背景

蜂蜜的抗菌、抗炎活性及其加速伤口愈合的能力使其成为手术伤口护理中一个有吸引力的选择。我们进行了一项随机临床试验,以比较蜂蜜敷料与传统敷料在美学效果方面的疗效。

患者与方法

在随机选择的整形外科患者中,双侧对称切口术后随机用传统敷料和蜂蜜敷料覆盖五天。由外科医生和患者根据视觉模拟量表对两侧的美学效果进行评分,并在术后三个月和六个月进行比较。

结果

研究期间对52例患者的72个对称切口进行了评估。接受蜂蜜敷料一侧在第三个月和第六个月时疤痕的平均宽度分别为3.64±0.83毫米和3.49±0.87毫米,对照组分别为5.43±0.05毫米和5.30±1.35毫米。Wilcoxon符号秩检验显示,在第三个月和第六个月时,蜂蜜敷料与传统敷料的效果存在显著差异(p<0.001)。

结论

使用蜂蜜敷料可改善手术伤口的愈合过程及其最终美学效果。

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