Serhal P F, Craft I L
Fertility and IVF Unit, Humana Hospital Wellington and University College, London.
Lancet. 1989 May 27;1(8648):1185-7. doi: 10.1016/s0140-6736(89)92762-1.
Oocyte donation was performed by gamete intrafallopian transfer in 61 women, 34 of whom were amenorrhoeic. The mean age of the donors was 32 years (range 23-38). Seventy-five treatment cycles gave 29 clinical pregnancies, of which 21 reached term, 3 continue, and 5 were lost (3 miscarriages, 1 tubal, and 1 cervical). 11 (38%) of the women who became pregnant were over 42 years old. When more than four oocytes were transferred, many of the pregnancies were multiple. 8 (38%) of the pregnancies that came to term were complicated by pre-eclamptic toxaemia. When oocytes are obtained from young women, the fertility potential is high irrespective of the recipient's age.
61名女性通过配子输卵管内移植进行了卵母细胞捐赠,其中34名女性闭经。捐赠者的平均年龄为32岁(范围23 - 38岁)。75个治疗周期中有29例临床妊娠,其中21例足月分娩,3例继续妊娠,5例妊娠丢失(3例流产,1例输卵管妊娠,1例宫颈妊娠)。怀孕的女性中有11名(38%)年龄超过42岁。当移植超过4个卵母细胞时,许多妊娠为多胎妊娠。足月分娩的妊娠中有8例(38%)并发先兆子痫。当从年轻女性获取卵母细胞时,无论接受者年龄如何,生育潜力都很高。