Trenkić Božinović Marija, Krasić Dragan, Katić Vuka, Krstić Miljan
Ophthalmology Clinic, University Medical Center, Niš, Serbia.
University of Niš, School of Medicine; Clinic of Maxillofacial Surgery Niš, Serbia.
Med Glas (Zenica). 2015 Feb;12(1):73-8.
To describe demographic and histomorphological characteristics of 139 patients with epithelial salivary gland tumors in the Southeastern Serbia population.
A total number of 139 patients with epithelial tumors arising in major and minor salivary glands in the period 2010-2012 was evaluated. After standard tissue proceeding, the routine haematoxylin-eosin (HE) and histochemical alcian blue-periodic acid-Schiff (AB - PAS) methods were used for histomorphological examination.
Among 139 patients, 102 (73.38%) had benign, and 37 (26.62%) malignant tumors. The majority of tumors were localized in the parotid gland, in 117 (84.17%) patients. Among benign tumors there were 50 (49.02%) pleomorphic adenoma, 48 (47.06%) Warthin's tumor, two (1.96%) myoepithelioma, and two (1.96%) oncocytoma. In the group of malignant tumors the most common was mucoepidermoid carcinoma, in 12 (32.43%) patients, carcinoma ex pleomorphic adenoma in six (16.22%), adenoid cystic carcinoma in five (13.51%), and oncocytic carcinoma in three (8.11%) patients.
Benign tumors were more common than malignant ones, with predominance of pleomorphic adenoma. Malignant tumors are less common than benign in the large salivary glands, and more common in the minor salivary glands. Histochemical AB-PAS method helps in the diagnosis of mucinous salivary gland carcinoma.
描述塞尔维亚东南部人群中139例上皮性涎腺肿瘤患者的人口统计学和组织形态学特征。
对2010年至2012年期间发生于大、小涎腺的139例上皮性肿瘤患者进行评估。经过标准的组织处理后，采用常规苏木精-伊红（HE）和组织化学阿尔辛蓝-过碘酸希夫（AB-PAS）方法进行组织形态学检查。
139例患者中，102例（73.38%）为良性肿瘤，37例（26.62%）为恶性肿瘤。大多数肿瘤位于腮腺，有117例（84.17%）患者。良性肿瘤中，多形性腺瘤50例（49.02%），沃辛瘤48例（47.06%），肌上皮瘤2例（1.96%），嗜酸性细胞瘤2例（1.96%）。恶性肿瘤组中最常见的是黏液表皮样癌，有12例（32.43%）患者，多形性腺瘤恶变6例（16.22%），腺样囊性癌5例（13.51%），嗜酸性细胞癌3例（8.11%）患者。
良性肿瘤比恶性肿瘤更常见，以多形性腺瘤为主。在大涎腺中，恶性肿瘤比良性肿瘤少见，而在小涎腺中更常见。组织化学AB-PAS方法有助于黏液性涎腺癌的诊断。
