从一个共同的前体中对多羟基吲哚里西啶酮和喹诺里西啶酮衍生物进行对映选择性合成。
Enantioselective synthesis of polyhydroxyindolizidinone and quinolizidinone derivatives from a common precursor.
机构信息
Department of Chemistry, University of Kalyani, Kalyani - 741235, West Bengal, India.
出版信息
Beilstein J Org Chem. 2014 Dec 22;10:3104-10. doi: 10.3762/bjoc.10.327. eCollection 2014.
Abstract
A concise asymmetric synthetic route to two new tetrahydroxyindolizidinone and quinolizidinone derivatives has been developed from a common intermediate which featured a highly selective dihydroxylation reaction and a RCM reaction as key steps.
摘要
从一个共同的中间体出发，开发了一种简洁的不对称合成路线，可得到两个新的四羟基吲哚里西啶酮和喹诺里西啶酮衍生物，其中关键步骤为高选择性的二羟化反应和 RCM 反应。
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