Yoon Kyu-Jin, Park Young-Bae, Park Young-Jae, Kim Min-Yong
Department of Diagnosis and Biofunctional Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Korea.
Chin J Integr Med. 2015 Jul;21(7):500-6. doi: 10.1007/s11655-015-2079-4. Epub 2015 Feb 12.
Lao Juan (LJ, ) is a syndrome described in Chinese medicine (CM) that manifests with fatigue, fever, spontaneous sweating, indigestion, work-induced pain, weakness of the limbs, and shortness of breath. The present study was conducted to examine the reliability and validity of a Lao Juan Questionnaire (LJQ).
A total of 151 outpatients and 73 normal subjects were asked to complete the LJQ. Seventy-three normal subjects were additionally asked to complete the Chalder Fatigue Scale (CFS). Twelve clinicians determined whether the 151 outpatients exhibited LJ or not. The internal consistency and construct validity for the LJQ were estimated using data from the outpatient subjects. The CFS data were used to examine the concurrent validity of the LJQ. Total LJQ scores and the clinicians᾿diagnoses of the outpatients were used to perform receiver operating characteristics (ROC) curve analyses and to define an optimum cut-off score for the LJQ.
The 19-item LJQ had satisfactory internal consistency (α=0.828) and concurrent validity, with significant correlations between the LJQ and the CFS subscales. In the test of construct validity using principal component analysis, a total of six factors were extracted, and the overall variance explained by all factors was 59.5%. In ROC curve analyses, the sensitivity, specificity, and area under the curve were 76.0%, 59.2%, and 0.709, respectively. The optimum cut-off score was defined as six points.
Our results suggest that the LJQ is a reliable and valid instrument for evaluating LJ.
劳倦（LJ）是中医描述的一种证候，表现为疲劳、发热、自汗、消化不良、劳作后疼痛、肢体无力和气短。本研究旨在检验劳倦问卷（LJQ）的信度和效度。
共151名门诊患者和73名正常受试者被要求完成LJQ。另外73名正常受试者被要求完成查尔德疲劳量表（CFS）。12名临床医生判断151名门诊患者是否表现为劳倦。使用门诊患者的数据评估LJQ的内部一致性和结构效度。CFS数据用于检验LJQ的同时效度。LJQ总分和门诊患者的临床医生诊断结果用于进行受试者工作特征（ROC）曲线分析，并确定LJQ的最佳截断分数。
19项的LJQ具有令人满意的内部一致性（α=0.828）和同时效度，LJQ与CFS各分量表之间存在显著相关性。在使用主成分分析的结构效度检验中，共提取了6个因子，所有因子解释的总方差为59.5%。在ROC曲线分析中，灵敏度、特异度和曲线下面积分别为76.0%、59.2%和0.709。最佳截断分数定义为6分。
我们的结果表明，LJQ是评估劳倦的一种可靠且有效的工具。
