Nomura Takashi, Inoue Yuichi, Nakashima Kenji
Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine , Tottori University.
Rinsho Shinkeigaku. 2014;54(12):987-90. doi: 10.5692/clinicalneurol.54.987.
Many patients with Parkinson's disease (PD) complain about sleep disturbances. These symptoms originate from motor symptoms, nocturnal problems, psychiatric symptoms, and other sleep disorders including Excessive daytime sleepiness (EDS), REM sleep behavior disorder (RBD), Restless legs syndrome (RLS), and Sleep apnea syndrome (SAS). Especially, RBD is paid attention to prodromal symptoms of PD. Also, one third of patients with PD have RBD symptoms. Moreover, RBD is one of aggravating factors of motor symptoms, autonomic dysfunctions, and dementia. Now, the evidence based medicine for sleep disturbances is lack in patients with PD. We need to evaluate various causes of sleep disturbances in detail and deal with individuals.
许多帕金森病(PD)患者抱怨存在睡眠障碍。这些症状源于运动症状、夜间问题、精神症状以及其他睡眠障碍,包括日间过度嗜睡(EDS)、快速眼动睡眠行为障碍(RBD)、不宁腿综合征(RLS)和睡眠呼吸暂停综合征(SAS)。特别是,RBD被视为PD的前驱症状。此外,三分之一的PD患者有RBD症状。而且,RBD是运动症状、自主神经功能障碍和痴呆的加重因素之一。目前,PD患者睡眠障碍的循证医学尚不完善。我们需要详细评估睡眠障碍的各种原因并针对个体进行处理。