在韩国分离的犬副流感病毒5型（CPIV-5）的分子特征
Molecular characteristics of canine parainfluenza viruses type 5 (CPIV-5) isolated in Korea.
作者信息
Oem Jae-Ku, Kim Seong-Hee, Kim Yeon-Hee, Lee Myoung-Heon, Lee Kyoung-Ki
机构信息
Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency, 480 Anyang-6-Dong, Anyang, 430-824, Republic of Korea.
出版信息
Can J Vet Res. 2015 Jan;79(1):64-7.
Abstract
Three canine parainfluenza viruses type 5 (CPIV-5) were isolated from lung tissues of 3 Korean dogs with mild pneumonia between 2008 and 2009. The isolates were fully sequenced and compared with published reference sequences. The size of the genome was 15 246 nucleotides long and no remarkable differences were found when compared with previously published reference sequences. In phylogenetic analysis based on the F and P genes, parainfluenza virus 5 (PIV-5) strains were divided into at least 3 subgroups. Three CPIV-5 strains were clustered with CPIV-5 T1, H22 and 78524 strains. All PIV-5 strains were independent of the host species, geographical distribution, and the isolated period.
摘要
2008年至2009年间，从3只患有轻度肺炎的韩国犬的肺组织中分离出3株犬副流感病毒5型（CPIV-5）。对分离株进行了全序列测定，并与已发表的参考序列进行比较。基因组大小为15246个核苷酸，与先前发表的参考序列相比未发现明显差异。在基于F基因和P基因的系统发育分析中，副流感病毒5型（PIV-5）毒株至少分为3个亚组。3株CPIV-5毒株与CPIV-5 T1、H22和78524毒株聚类。所有PIV-5毒株均与宿主物种、地理分布和分离时间无关。
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