Jiang Ning, Wang Enyu, Guo Donghua, Wang Xin, Su Mingjun, Kong Fanzhi, Yuan Dongwei, Zhai Junjun, Sun Dongbo
Laboratory for the Prevention and Control of Swine Infectious Diseases, College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, No. 5 Xinfeng Road, Sartu District, Daqing 163319, P.R. China.
J Vet Med Sci. 2018 Apr 18;80(4):590-593. doi: 10.1292/jvms.17-0581. Epub 2018 Feb 20.
Recently, parainfluenza virus 5 (PIV5) infection has been increasingly reported in mammals. In this study, five PIV5 strains were isolated from diarrhea-affected piglets from four provinces or municipalities in China. An F-gene-based phylogenetic tree indicated that the five isolated strains were closely related to the PIV5 strain ZJQ-221 from a lesser panda in China, and the PIV5 strain 1168-1 from a dog in South Korea. The new isolates differed genetically from other pig, calf, rhesus macaque kidney cells, human, and dog PIV5 reference strains. Our study reveals the presence of PIV5 in intestinal tissue samples collected from diarrhea-affected piglets, and provides novel information regarding the epidemiology and tissue tropism of PIV5.
最近，在哺乳动物中越来越多地报道了副流感病毒5型（PIV5）感染。在本研究中，从中国四个省或直辖市的腹泻仔猪中分离出五株PIV5毒株。基于F基因的系统发育树表明，这五株分离株与来自中国一只小熊猫的PIV5毒株ZJQ - 221以及来自韩国一只狗的PIV5毒株1168 - 1密切相关。这些新分离株在基因上与其他猪、小牛、恒河猴肾细胞、人以及狗的PIV5参考毒株不同。我们的研究揭示了在腹泻仔猪的肠道组织样本中存在PIV5，并提供了关于PIV5流行病学和组织嗜性的新信息。
