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新型化合物被发现是偶然的细胞培养污染物。

Novel Discovered as Accidental Cell Culture Contaminant.

机构信息

Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66053, USA.

Institute for Information Transmission Problems of the Russian Academy of Sciences, Moscow 127051, Russia.

出版信息

Viruses. 2019 Aug 23;11(9):777. doi: 10.3390/v11090777.

DOI:10.3390/v11090777
PMID:31450796
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6783914/
Abstract

A distinct Russian (PIV5) was detected in cell culture exhibiting cytopathic effect and hypothesized to be contaminated by a scientist with respiratory symptoms. The identification of the divergent strain indicated a lack of knowledge on the diversity of PIV5 strains and calls for surveillance of global PIV5 strains.

摘要

在细胞培养中检测到一种独特的俄罗斯（PIV5）病毒，具有细胞病变效应，并假设是一位有呼吸道症状的科学家污染的。这种变异株的鉴定表明，人们对 PIV5 株的多样性缺乏了解，因此需要对全球的 PIV5 株进行监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ae/6783914/394a6de7a108/viruses-11-00777-g003a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ae/6783914/008d38f28344/viruses-11-00777-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ae/6783914/8f3c9ffcd02a/viruses-11-00777-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ae/6783914/394a6de7a108/viruses-11-00777-g003a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ae/6783914/008d38f28344/viruses-11-00777-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ae/6783914/8f3c9ffcd02a/viruses-11-00777-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ae/6783914/394a6de7a108/viruses-11-00777-g003a.jpg

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Pathogens. 2018 Apr 20;7(2):46. doi: 10.3390/pathogens7020046.
2
A porcine enterovirus G associated with enteric disease contains a novel papain-like cysteine protease.一种与肠道疾病相关的猪肠道病毒G含有一种新型木瓜蛋白酶样半胱氨酸蛋白酶。
J Gen Virol. 2017 Jun;98(6):1305-1310. doi: 10.1099/jgv.0.000799. Epub 2017 Jun 8.
3
First complete genome sequence of parainfluenza virus 5 isolated from lesser panda.
公共测序数据中的隐藏病毒序列与未来新发传染病预警。
mBio. 2021 Aug 31;12(4):e0163821. doi: 10.1128/mBio.01638-21. Epub 2021 Aug 17.
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Emerg Infect Dis. 2015 Dec;21(12):2242-4. doi: 10.3201/eid2112.141111.
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