Di Venere D, Corsalini M, Stefanachi G, Tafuri S, De Tommaso M, Cervinara F, Re A, Pettini F
Dental School, University of Bari, Bari, Italy.
Department of Biomedical Sciences and Human Oncology, University of Bari, Bari, Italy.
Open Dent J. 2015 Jan 30;9:9-14. doi: 10.2174/1874210601509010009. eCollection 2015.
Fibromyalgia (FM) is a rheumatic disease which affects fibrous tissues and muscles; it is characterized by chronic pain and it is often associated with craniomandibular disorders (CMD). 31 patients were assessed from March 2012 to October 2012 through the administration of specific questionnaires and following neurologic and gnatologic assessment. A relevant corre-lation between FM and CMD emerges from the present study, as 80.6% of our patients report CMD symptoms with high prevalence of myofascial pain (84%). Multivariate regression analysis revealed that the patients in the present study did not differ in score of quality of life questionnaires from patients with fibromyalgia. The neuropathic pain diagnostic question-naire (DN4) scores were positively affected by belonging to group II of Research Diagnostic Criteria of Temporomandibular Disorders (RDC/ TDM) classification, suggesting the possibility of a neuropathic component in chronic pain in this CMD group, as already speculated in our study on the correlation between burning mouth syndrome and CMD and by other au-thors in studies on chronic low back pain. However, further clinic and instrumental studies are needed in order to test this as-sumption.
纤维肌痛（FM）是一种影响纤维组织和肌肉的风湿性疾病；其特征为慢性疼痛，且常与颅下颌疾病（CMD）相关。2012年3月至2012年10月期间，通过发放特定问卷以及进行神经学和口腔科评估，对31例患者进行了评估。本研究显示FM与CMD之间存在显著相关性，因为80.6%的患者报告有CMD症状，其中肌筋膜疼痛的患病率很高（84%）。多因素回归分析表明，本研究中的患者在生活质量问卷得分方面与纤维肌痛患者并无差异。神经性疼痛诊断问卷（DN4）得分受颞下颌关节紊乱研究诊断标准（RDC/ TMD）分类中II组的影响呈阳性，这表明在该CMD组的慢性疼痛中可能存在神经病变成分，正如我们在关于灼口综合征与CMD相关性的研究以及其他作者在关于慢性下腰痛的研究中所推测的那样。然而，需要进一步的临床和仪器研究来验证这一假设。
