Amaral Márcio-Bruno-Figueiredo, Souto Giovanna-Ribeiro, Horta Martinho-Campolina-Rebello, Gomez Ricardo-Santiago, Mesquita Ricardo-Alves
Department of Oral Surgery and Pathology. School of Dentistry. Universidade Federal de Minas Gerais. Belo Horizonte - MG, Brazil.
Department of Dentistry, Pontifícia Universidade Católica de Minas Gerais. Belo Horizonte - MG, Brazil.
J Clin Exp Dent. 2014 Dec 1;6(5):e588-91. doi: 10.4317/jced.51440. eCollection 2014 Dec.
Odontogenic fibroma (OF) is a rare benign odontogenic neoplasm that is most commonly found in the mandibular/premolar region of female patients in the second to fourth decades of life. Well-defined radiolucent lesions that may induce root resorption are normally observed. Rare variants of OF have been described in the prior literature, including references to: 1) giant cell lesions, 2) amyloid-like protein deposition, and 3) ossifying variants. Immunohistochemistry can contribute to understanding the biological behavior and the pathogenesis of OF. Therefore, this case report aimed to describe a new case of ossifying OF and discuss the histopathology and immunohistochemical features. Key words:Odontogenic fibroma, jaw tumors, ossifying variant.
牙源性纤维瘤（OF）是一种罕见的良性牙源性肿瘤，最常见于20至40岁女性患者的下颌/前磨牙区。通常可观察到边界清晰的透射性病变，可能会导致牙根吸收。先前的文献中已描述了OF的罕见变异型，包括：1）巨细胞病变，2）淀粉样蛋白沉积，以及3）骨化变异型。免疫组织化学有助于了解OF的生物学行为和发病机制。因此，本病例报告旨在描述一例骨化性OF的新病例，并讨论其组织病理学和免疫组织化学特征。关键词：牙源性纤维瘤，颌骨肿瘤，骨化变异型。
