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1992 - 2012年糖尿病死亡率及严重并发症发生率变化的原因

Causes of the change in the rates of mortality and severe complications of diabetes mellitus: 1992-2012.

作者信息

Yashkin Arseniy P, Picone Gabriel, Sloan Frank

机构信息

*Department of Economics, Duke University, Durham, NC †Department of Economics, University of South Florida, Tampa, FL.

出版信息

Med Care. 2015 Mar;53(3):268-75. doi: 10.1097/MLR.0000000000000309.

Abstract

OBJECTIVE

To quantify the causes of the changes in the rates of mortality and select severe complications of diabetes mellitus, type 2 (T2D) among the elderly between 1992 and 2012.

RESEARCH DESIGN

A retrospective cohort study design based on Medicare 5% administrative claims data from 1992 to 2012 was used. Traditional fee-for-service Medicare beneficiaries, age 65 and older, diagnosed with T2D and living in the United States between 1992 and 2012 were included in the study. Blinder-Oaxaca decomposition was used to quantify the potential causes of the change in the rates of death, congestive heart failure and/or acute myocardial infarction, stroke, amputation of lower extremity and end-stage renal disease between 1992 and 2012.

RESULTS

The number of beneficiaries in the analysis sample diagnosed with T2D increased from 152,191 in 1992 to 289,443 in 2012. Over the same time period, rates of mortality decreased by 1.2, congestive heart failure and/or acute myocardial infarction by 2.6, stroke by 1.6, amputation by 0.6 while rates of end-stage renal disease increased by 1.5 percentage points. Improvements in the management of precursor conditions and utilization of recommended healthcare services, not population composition, were the primary causes of the change.

CONCLUSIONS

With the exception of end-stage renal disease, outcomes among Medicare beneficiaries diagnosed with T2D improved. Analysis suggests that persons diagnosed with T2D are living longer with fewer severe complications. Much of the improvement in outcomes likely reflects more regular contact with health professionals and better management of care.

摘要

目的

量化1992年至2012年间老年人中2型糖尿病(T2D)死亡率及特定严重并发症变化的原因。

研究设计

采用基于1992年至2012年医疗保险5%行政索赔数据的回顾性队列研究设计。研究纳入了1992年至2012年间年龄在65岁及以上、被诊断为T2D且居住在美国的传统按服务收费医疗保险受益人。采用布林德-奥瓦卡分解法来量化1992年至2012年间死亡、充血性心力衰竭和/或急性心肌梗死、中风、下肢截肢及终末期肾病发生率变化的潜在原因。

结果

分析样本中被诊断为T2D的受益人数从1992年的152,191人增加到2012年的289,443人。在同一时期,死亡率下降了1.2个百分点,充血性心力衰竭和/或急性心肌梗死下降了2.6个百分点,中风下降了1.6个百分点,截肢下降了0.6个百分点,而终末期肾病的发生率增加了1.5个百分点。前期疾病管理的改善和推荐医疗服务的利用,而非人群构成,是变化的主要原因。

结论

除终末期肾病外,被诊断为T2D的医疗保险受益人的预后有所改善。分析表明,被诊断为T2D的人寿命更长,严重并发症更少。预后的改善很大程度上可能反映了与医疗专业人员更频繁的接触和更好的护理管理。

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