Han Zhen-xiang, Qi Li-li, Chu Li-xi, Cai Wei-qing, Chen Xue-fen, Huang Jing-yi, Zhang Hui-yan
Zhongguo Zhen Jiu. 2014 Nov;34(11):1067-72.
To optimize the therapeutic programs for periarthritis of shoulder treated with acupuncture, moxibustion and kinetohterapy with orthogonal design method adopted.
The orthogonal design table of L8 (2(7)) hierarchical principle was used to randomly divide 192 patients of periarthritis of shoulder into 8 groups, 24 cases in each one. Separately, 4 factors and each different 2 levels were adopted in treatment, named acupuncture timing (factor A: A, acute stage, A2 adhesion stage), acupoint combination (factor B: B, local acupoints, B2 local acupoints and distal acupoints along meridians), filiform needling and warm needling therapy (factor C: C1 acupuncture with filiform needle, CZ acupuncture with filiform needle and warm needling therapy) and positive functional exercise (factor D: D1 without positive functional exercise, D2 with positive functional exercise). The treatment was given once a day, 10 treatments made one session and 2 sessions were required totally. The time points of observation were the point after 1 session of treatment and after 2 sessions of treatment. The short-form McGill pain questionnaire (MPQ) and shoulder joint motor disturbance score were adopted for evaluation.
In the orthogonal design analysis, taking the hierarchical factors into consideration, the age was considered as the main factor in the evaluation of shoulder pain and shoulder motor disturbance (P<0.01), and the shoulder function grade apparently impacted pain evaluation and the efficacy on shoulder motor disturbance (P<0.01). The best combination of 4 factors and 2 levels were A1B1CzD2 and A2BC2D2. SAS statistical analysis showed that at acute stage and adhesion stage, CZ Dz , meaning acupuncture with fifiform needling and warm needling therapy combined with positive functional exercise, is the main factor of the improvements of shoulder motor function (P<0.05).
For periarthritis of shoulder at acute stage, the combined therapy of acupuncture at local acupoints, warm needling and positive functional exercise is adopted. At chronic stage, the combined therapy of acupuncture at local acupoints and distal acupoints, acupuncture with filiform needle and warm needling and positive functional exercise is the best program. Additionally, in clinical treatment, the patients' age, sex, shoulder joint function and duration of treatment should be considered comprehensively for the impacts on the efficacy.
采用正交设计方法优化针灸、艾灸及运动疗法治疗肩周炎的方案。
运用L8(2(7))分层正交设计表,将192例肩周炎患者随机分为8组,每组24例。治疗采用4个因素,各因素设置2个不同水平,分别为针刺时机(因素A:A1急性期,A2粘连期)、穴位组合(因素B:B1局部穴位,B2局部穴位加循经远端穴位)、毫针针刺与温针疗法(因素C:C1毫针针刺,C2毫针针刺加温和灸)及积极功能锻炼(因素D:D1不进行积极功能锻炼,D2进行积极功能锻炼)。每天治疗1次,10次为1个疗程,共需2个疗程。观察时间点为治疗1个疗程后及治疗2个疗程后。采用简化McGill疼痛问卷(MPQ)及肩关节运动障碍评分进行评价。
在正交设计分析中,综合分层因素考虑,年龄是影响肩部疼痛及肩部运动障碍评估的主要因素(P<0.01),肩关节功能分级对疼痛评估及肩部运动障碍疗效有明显影响(P<0.01)。4个因素2个水平的最佳组合为A1B1C2D2和A2B1C2D2。SAS统计分析显示,在急性期和粘连期,C2D2,即毫针针刺加温和灸联合积极功能锻炼,是改善肩部运动功能的主要因素(P<0.05)。
肩周炎急性期采用局部穴位针刺、温针及积极功能锻炼的联合疗法;慢性期采用局部穴位与远端穴位针刺、毫针针刺加温和灸及积极功能锻炼的联合疗法为最佳方案。此外,在临床治疗中,应综合考虑患者年龄、性别、肩关节功能及病程对疗效的影响。