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手动针刺与激光针刺对深度Ⅱ度烧伤大鼠伤口愈合的影响。

Effect of Manual Acupuncture and Laser Acupuncture on Wound Closure in Rat with Deep Partial Thickness Burn Injury.

作者信息

Ishak Andy, Jusuf Ahmad Aulia, Simadibrata Christina Lanny, Barasila Atikah Chalida, Novita Risqa

机构信息

Medical Acupuncture Specialist Program and Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.

Department of Histology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.

出版信息

Med Acupunct. 2022 Aug 1;34(4):240-250. doi: 10.1089/acu.2021.0083. Epub 2022 Aug 17.

DOI:10.1089/acu.2021.0083
PMID:36051408
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9419944/
Abstract

BACKGROUND

Burns are defined as tissue damage that occurs as a result of the action of heat. Although many advanced treatments have been made in burn therapy, slow wound healing remains a challenge in burn treatment. Acupuncture can accelerate burn healing through its anti-inflammatory effect, increasing re-epithelialization and angiogenesis.

OBJECTIVES

This study assessed the effect of manual acupuncture and laser acupuncture on the healing of burns that were observed macroscopically and microscopically.

METHODS

Thirty-six male Wistar rats with deep partial thickness burns were randomly divided into control group ( = 12), acupuncture group ( = 12), and laser acupuncture group ( = 12). Wound measurements and treatments were given every 2 days for 14 days.

RESULTS

On the 14th day of macroscopic evaluations, there was a significant difference ( = 0.009) between the acupuncture group (66.96 ± 9.17) and the control group (49.93 ± 9.15), and a significant difference ( = 0.009) between laser acupuncture group (72.48 ± 14.62) and the control group. However, there was no significant difference ( = 0.451) between acupuncture and laser acupuncture groups. On the 14th day of microscopic evaluations, there was a significant difference ( < 0.001) between the acupuncture group (16.17 ± 1.17) and the control group (10.33 ± 1.21), and a significant difference ( = 0.004) between the laser acupuncture group (17.83 ± 1.47) and the control group. However, there was no significant difference ( = 0.058) between acupuncture and laser acupuncture groups.

CONCLUSION

The results showed that either acupuncture therapy or laser acupuncture therapy could be used as an adjunct therapy to accelerate burn healing.

摘要

背景

烧伤被定义为因热作用而发生的组织损伤。尽管在烧伤治疗方面已经取得了许多先进的治疗方法,但伤口愈合缓慢仍然是烧伤治疗中的一个挑战。针灸可以通过其抗炎作用、促进再上皮化和血管生成来加速烧伤愈合。

目的

本研究评估了手动针灸和激光针灸对烧伤愈合的宏观和微观观察效果。

方法

将36只雄性Wistar大鼠深度部分厚度烧伤,随机分为对照组(n = 12)、针灸组(n = 12)和激光针灸组(n = 12)。每2天进行伤口测量和治疗,持续14天。

结果

在宏观评估的第14天,针灸组(66.96±9.17)与对照组(49.93±9.15)之间存在显著差异(P = 0.009),激光针灸组(72.48±14.62)与对照组之间也存在显著差异(P = 0.009)。然而,针灸组和激光针灸组之间没有显著差异(P = 0.451)。在微观评估的第14天,针灸组(16.17±1.17)与对照组(10.33±1.21)之间存在显著差异(P < 0.001),激光针灸组(17.83±1.47)与对照组之间也存在显著差异(P = 0.004)。然而,针灸组和激光针灸组之间没有显著差异(P = 0.058)。

结论

结果表明,针灸疗法或激光针灸疗法均可作为辅助疗法来加速烧伤愈合。

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Increased Rate of Long-term Mortality Among Burn Survivors: A Population-based Matched Cohort Study.烧伤幸存者长期死亡率升高:基于人群的匹配队列研究。
Ann Surg. 2019 Jun;269(6):1192-1199. doi: 10.1097/SLA.0000000000002722.
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Adv Drug Deliv Rev. 2018 Jan 1;123:3-17. doi: 10.1016/j.addr.2017.09.018. Epub 2017 Sep 20.
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