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土耳其伊斯坦布尔老年人群中变应性鼻炎的临床及变应性致敏特征

Clinical and allergic sensitization characteristics of allergic rhinitis among the elderly population in Istanbul, Turkey.

作者信息

Ozturk Ayse Bilge, Ozyigit Leyla Pur, Olmez Merve Ozata

机构信息

Allergy and Immunology Department, Koç University Hospital, Istanbul, Turkey.

Allergy and Immunology Department, Koç University School of Medicine, Istanbul, Turkey.

出版信息

Eur Arch Otorhinolaryngol. 2015 Apr;272(4):1033-1035. doi: 10.1007/s00405-015-3552-6. Epub 2015 Feb 14.

DOI:10.1007/s00405-015-3552-6
PMID:25680346
Abstract

Prevalence of allergic rhinitis (AR) in elderly population in Turkey is not known. Studies on the prevalence and features of allergy in older adults are needed to identify safe and effective diagnostic/therapeutic methods for elderly AR patients. We aimed to identify the clinical and allergic characteristics of sensitization to aeroallergens among individuals aged ≥60 years with allergic rhinitis admitted to an allergy outpatient clinic in Istanbul. Of 109 patients, 33.9 % were atopic. Sixty-five percent of subjects were sensitized to Dermatophagoides pteronyssinus, 17 % to a grass-pollen mixture, 8 % to Aspergillus fumigatus, and 8 % to Blattella germanica. There was no difference between mono- and polysensitized patients in terms of the duration of rhinitis and symptom severity. No significant difference was observed between the two groups according to age, sex, smoking status, AR onset (<40 or ≥40 years), or duration/severity of disease. There was no significant difference between the two groups in the prevalence of asthma and conjunctivitis, (p = 0.256). Atopic dermatitis/eczema was more prevalent in those with AR (p = 0.046). Clinical characteristics of AR in the elderly could be different from those in non-allergic patients, and the prevalence of allergy may be higher than expected.

摘要

土耳其老年人群中过敏性鼻炎(AR)的患病率尚不清楚。需要开展关于老年人过敏患病率及特征的研究,以确定针对老年AR患者安全有效的诊断/治疗方法。我们旨在确定伊斯坦布尔一家过敏门诊收治的年龄≥60岁的过敏性鼻炎患者对气传变应原致敏的临床及过敏特征。在109例患者中,33.9%为特应性体质。65%的受试者对屋尘螨致敏,17%对草花粉混合物致敏,8%对烟曲霉致敏,8%对德国小蠊致敏。单致敏和多致敏患者在鼻炎病程和症状严重程度方面无差异。根据年龄、性别、吸烟状况、AR起病年龄(<40岁或≥40岁)或疾病病程/严重程度,两组之间未观察到显著差异。两组在哮喘和结膜炎患病率方面无显著差异(p = 0.256)。特应性皮炎/湿疹在AR患者中更为常见(p = 0.046)。老年人AR的临床特征可能与非过敏患者不同,且过敏患病率可能高于预期。

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