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土耳其黑海东部地区过敏性鼻炎患者对屋尘螨的高致敏性:一项回顾性研究。

High sensitization to house-dust mites in patients with allergic rhinitis in the eastern Black Sea region of Turkey: A retrospective study.

作者信息

Coskun Zerrin Ozergin, Erdivanlı Ozlem Celebi, Kazıkdas Kadir Çagdas, Terzi Suat, Sahin Unal, Ozgur Abdulkadir, Demirci Munir, Dursun Engin, Cingi Cemal

机构信息

Department of Otorhinolaryngology, Recep Tayyip Erdogan University Medical Faculty, Rize, Turkey.

出版信息

Am J Rhinol Allergy. 2016 Sep 1;30(5):351-355. doi: 10.2500/ajra.2016.30.4353. Epub 2016 Jul 1.

DOI:10.2500/ajra.2016.30.4353
PMID:27465310
Abstract

OBJECTIVES

Identification of the most common aeroallergens to which patients are sensitized in a specific area is important in the diagnosis and treatment of allergic rhinitis (AR). We determined the distribution of aeroallergens, detected by skin-prick tests (SPT), in adult patients with AR in the Eastern Black Sea region of Turkey and compared the results with the other regions of Turkey and in the world.

METHODS

The medical records of SPT performed on 1457 patients with symptoms of AR (with regard to the Allergic Rhinitis and its Impact on Asthma 2008 guidelines) between March 2010 and March 2013 were analyzed retrospectively. SPT were carried out with the same panel, which included grass; weeds; trees; mold; epidermal mixtures; and with two house-dust mite (HDM) extracts, Dermatophagoides pteronyssinus and Dermatophagoides farinae.

RESULTS

In 1229 of 1457 patients (84.4%), there were positive reactions for at least one aeroallergen on the SPT. The most common aeroallergen was the HDM D. pteronyssinus (84% [n = 1033]) followed by D. farinae (78.2% [n = 962]). Grass pollen sensitivity (70.8% [n = 871]) was higher than tree or weed pollen sensitivity in this region.

CONCLUSIONS

The most common aeroallergens in AR are HDMs of D. pteronyssinus and D. farinae in the Eastern Black Sea region in Turkey. Our study may help in developing environmental control strategies for AR.

摘要

目的

确定特定地区患者致敏的最常见空气过敏原对于过敏性鼻炎(AR)的诊断和治疗很重要。我们测定了土耳其黑海东部地区成年AR患者通过皮肤点刺试验(SPT)检测到的空气过敏原分布,并将结果与土耳其其他地区及世界其他地区进行比较。

方法

回顾性分析2010年3月至2013年3月期间对1457例有AR症状患者(符合2008年变应性鼻炎及其对哮喘的影响指南)进行SPT的病历。使用同一组过敏原进行SPT,包括草;杂草;树木;霉菌;表皮混合物;以及两种屋尘螨(HDM)提取物,即尘螨和粉螨。

结果

1457例患者中有1229例(84.4%)在SPT中对至少一种空气过敏原呈阳性反应。最常见的空气过敏原是尘螨(84%[n = 1033]),其次是粉螨(78.2%[n = 962])。该地区草花粉敏感性(70.8%[n = 871])高于树或杂草花粉敏感性。

结论

在土耳其黑海东部地区,AR中最常见的空气过敏原是尘螨和粉螨。我们的研究可能有助于制定AR的环境控制策略。

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