Linde Y W
Department of Dermatology, Södersjukhuset, Stockholm, Sweden.
Acta Derm Venereol. 1989;69(4):311-4.
A common finding in patients with atopic dermatitis is the occurrence of 'dry' skin on non-eczematous regions. 'Dry' skin is here defined as a clinical condition meaning a rough, finely scaling non-inflamed skin surface. The frequency and extension of 'dry' skin were examined in 50 patients with atopic dermatitis and were compared with those in 50 non-atopics. A discrepancy was found in both groups between the subjective opinion of the presence of 'dry' skin and the objectively noted 'dry' skin. Among the atopics, 48% were found to have 'dry' skin compared with 14% among the controls (p less than 0.01). The most frequent location of 'dry' skin in both groups was the back. Intolerance to wool was found to be significantly high (p less than 0.01) in the atopic group, although it was also quite common in non-atopics. In order to correlate the clinical observation to skin morphology, a replica-technique was used to visualize the surface of 'dry' skin in the scanning electron microscope.
特应性皮炎患者的一个常见表现是在非湿疹区域出现“干性”皮肤。此处“干性”皮肤定义为一种临床状况，即皮肤表面粗糙、有细微鳞屑且无炎症。对50例特应性皮炎患者的“干性”皮肤出现频率及范围进行了检查，并与50例非特应性个体进行了比较。两组在“干性”皮肤存在的主观判断与客观记录之间均存在差异。特应性个体中，48%被发现有“干性”皮肤，而对照组中这一比例为14%（p<0.01）。两组中“干性”皮肤最常见的部位是背部。特应性组对羊毛不耐受的比例显著较高（p<0.01），尽管在非特应性个体中也较为常见。为了将临床观察与皮肤形态学相关联，采用复型技术在扫描电子显微镜下观察“干性”皮肤表面。
