Hein M D, Monchik J M, Jackson I M
Department of Medicine, Rhode Island Hospital, Providence 02903.
J Endocrinol Invest. 1989 Apr;12(4):265-7. doi: 10.1007/BF03349981.
The diagnosis of pheochromocytoma in a 48-year-old man was confirmed by elevated catecholamine secretion and a left adrenal mass on computerized tomography. Because of a plausible family history for Multiple Endocrine Neoplasia Type II, a calcitonin level was determined which was elevated, and pentagastrin stimulation caused a 235% increase. These findings normalized following surgical removal of the single adrenal tumor. It is concluded that pentagastrin stimulation of calcitonin is not necessarily diagnostic of medullary thyroid carcinoma, and such a response in a patient presenting with pheochromocytoma may not indicate underlying Multiple Endocrine Neoplasia Type II.
一名48岁男性患者，通过儿茶酚胺分泌升高及计算机断层扫描显示左肾上腺肿块确诊为嗜铬细胞瘤。由于其家族有患II型多发性内分泌腺瘤病的可能，故测定了降钙素水平，结果显示升高，且五肽胃泌素刺激后降钙素水平升高了235%。手术切除单个肾上腺肿瘤后，这些结果恢复正常。得出的结论是，五肽胃泌素刺激降钙素不一定能诊断甲状腺髓样癌，且在患有嗜铬细胞瘤的患者中出现这种反应可能并不表明存在潜在的II型多发性内分泌腺瘤病。
