Sun Ke-Kang, Yang Dong, Gan Mingqiang, Wu Xiao-Yang
Department of Gastrointestinal Surgery, Kunshan First People's Hospital Affiliated to Jiangsu University, Kunshan, Jiangsu 215300, P.R. China ; Multiple Disciplinary Team (MDT) of Gastrointestinal Cancer, Kunshan First People's Hospital Affiliated to Jiangsu University, Kunshan, Jiangsu 215300, P.R. China.
Department of Gastrointestinal Surgery, Kunshan First People's Hospital Affiliated to Jiangsu University, Kunshan, Jiangsu 215300, P.R. China.
Oncol Lett. 2015 Mar;9(3):1380-1382. doi: 10.3892/ol.2014.2805. Epub 2014 Dec 17.
The incidence of intussusception is low in adults, particularly in the descending colon, due to the anatomical attachment of the descending colon to the retroperitoneum. Signet ring cell histology represents ~1% of colon adenocarcinomas and is associated with young patients and a poor clinical outcome. The present study describes a case of descending colo-colonic intussusception caused by signet ring cell carcinoma in a 27-year-old male. The patient presented with a history of intermittent left upper-quadrant abdominal pain for more than six months without any evident etiology. A computed tomography scan of the abdomen revealed left-sided colo-colonic intussusception. Upon laparotomy, a left hemicolectomy was performed according to intraoperative frozen-section pathology. Post-operative pathological evaluation revealed signet ring cell carcinoma invasion of the serosa, and 31.8% (7/22) of the regional lymph nodes were positive for cancerous cells. The post-operative course was uneventful and the patient was discharged on the tenth post-operative day.
由于降结肠与腹膜后组织的解剖附着关系，成人肠套叠的发生率较低，尤其是在降结肠。印戒细胞组织学类型约占结肠腺癌的1%，与年轻患者及不良临床预后相关。本研究描述了一例27岁男性因印戒细胞癌导致降结肠-结肠套叠的病例。该患者有超过六个月的间歇性左上腹腹痛病史，无明显病因。腹部计算机断层扫描显示左侧结肠-结肠套叠。剖腹手术时，根据术中冰冻切片病理结果进行了左半结肠切除术。术后病理评估显示印戒细胞癌侵犯浆膜，31.8%（7/22）的区域淋巴结有癌细胞转移。术后病程平稳，患者于术后第十天出院。
