Poser Steven W, Androutsellis-Theotokis Andreas
Stem Cell Res Ther. 2014 Nov 17;5(6):127. doi: 10.1186/scrt517.
There is a growing interest in the therapeutic utility of compounds derived from Curcuma longa, an herb of the Zingiberaceae family that has been part of traditional medicine for centuries. Recent reports suggest that bioactive compounds isolated from the rhizome of these plants can address two key aspects of brain injury following stroke that must be dealt with for functional recovery to occur: the moderation of neuroinflammation, and the mobilization of endogenous stem cells resident in the nervous system. Defining their mechanism of action remains a question, but emerging evidence may point towards one shared with more classic modulators of neural stem cell proliferation and survival.
人们对源自姜黄的化合物的治疗效用越来越感兴趣。姜黄是姜科的一种草本植物，几个世纪以来一直是传统医学的一部分。最近的报告表明，从这些植物的根茎中分离出的生物活性化合物可以解决中风后脑损伤的两个关键方面，这两个方面是功能恢复所必须解决的：减轻神经炎症，以及动员存在于神经系统中的内源性干细胞。确定它们的作用机制仍然是一个问题，但新出现的证据可能指向一种与更经典的神经干细胞增殖和存活调节剂共有的机制。
