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腰椎内镜下经椎间孔减压、椎间融合及经皮椎弓根螺钉植入术:病例系列报告

Endoscopic transforaminal decompression, interbody fusion, and percutaneous pedicle screw implantation of the lumbar spine: A case series report.

作者信息

Osman Said G

机构信息

American Spine Center, Frederick, MD.

出版信息

Int J Spine Surg. 2012 Dec 1;6:157-66. doi: 10.1016/j.ijsp.2012.04.001. eCollection 2012.

Abstract

BACKGROUND

On the basis of the experiences gained from conventional open spinal procedures, a long list of desirable objectives have emerged with the evolution of the lesser invasive spinal procedures. At the top of that list is the desire to minimize the trauma of surgery. The rest of the objectives, which include reductions of operating time, surgical blood loss, hospital stay, postoperative narcotic medication, convalescence, complication rates, and escalating health care costs, as well as the desire of elderly patients to continue rigorous physical activities, largely depend on the ability to minimize the trauma of surgery. The purpose of this study was to investigate the feasibility of the least invasive lumbar decompression, interbody fusion and percutaneous pedicle screw implantation, to minimize surgical trauma without compromising the quality of the treatment outcome, as well as to minimize risk of complications.

METHODS

In this case series, 60 patients with diagnoses of degenerative disc disease, degenerative motion segments with stenosis, and spondylolisthesis, in whom nonoperative treatments failed, were treated with endoscopic transforaminal decompression and interbody fusion by 1 surgeon in 2 centers. The outcome measures were as follows: operating time, intraoperative blood loss, hospital stay, Visual Analogue Scale (VAS) scores for back and leg pain, scores on the Roland-Morris Disability Questionnaire, and postoperative imaging studies. A consecutive series of patients who met the treatment criteria completed VAS forms and Roland-Morris questionnaires preoperatively. Surgical procedures included arthroscopic decompression of the foramina and the discs; endplate preparation and implantation of allograft bone chips and bone morphogenetic protein 2 on absorbable collagen sponge into the disc space; and percutaneous implantation of pedicle screws. Postoperatively, the patients again completed the VAS forms and Roland-Morris questionnaires. Their charts were reviewed for office notes, operative notes, hospital stay, medications, and imaging studies. The latest X-ray and computed tomography scan films were reviewed and analyzed. Patients were followed up for a minimum of 6 months. The literature was reviewed for comparison of outcomes.

RESULTS

Sixty patients met the inclusion criteria. The mean age was 52.8 years. The duration of illness averaged 5 years. Follow-up ranged from 6 to 25 months, with a mean of 12 months. Preoperative diagnoses included degenerative disc disease, degenerative motion segments with stenosis, and spondylolisthesis. The mean time in the operating room was 2 hours 54 minutes. Estimated blood loss averaged 57.6 mL. The duration of the hospital stay averaged 2.6 days. Preoperative back pain and leg pain were significantly reduced (P < .005). Forty-seven imaging studies obtained at the last visit, including X-ray and computed tomography scans, showed solid fusion in 28 patients (59.6%), stable fixation in 17 (36.2%), and osteolysis around the pedicle screws in 2 (4.2%). All patients had improvement of motor function, whereas 2 patients complained of residual numbness. In addition, 8 patients (13%) complained of residual discomfort on extension of the lumbar spine. Two patients had pedicle screw-related complications requiring surgery. A review of the literature showed that endoscopic transforaminal decompression and interbody fusion performed better than open transforaminal lumbar interbody fusion/posterior lumbar interbody fusion, minimally invasive transforaminal lumbar interbody fusion, and extreme lateral lumbar interbody fusion, with regard to most parameters studied.

CONCLUSIONS

The endoscopic transforaminal lumbar decompression, interbody fusion, and percutaneous pedicle screw instrumentation consistently produced satisfactory results in all demographics. It performed better than the alternative procedures for most parameters studied.

摘要

背景

基于传统开放性脊柱手术所积累的经验,随着微创脊柱手术的发展,出现了一系列理想的目标。其中首要目标是将手术创伤降至最低。其余目标,包括缩短手术时间、减少手术失血、缩短住院时间、减少术后麻醉药物使用、缩短康复期、降低并发症发生率以及控制不断攀升的医疗费用,同时满足老年患者继续进行高强度体育活动的愿望,很大程度上都依赖于将手术创伤降至最低的能力。本研究的目的是探讨微创腰椎减压、椎间融合及经皮椎弓根螺钉植入术的可行性,在不影响治疗效果质量的前提下将手术创伤降至最低,并降低并发症风险。

方法

在本病例系列研究中,60例诊断为椎间盘退变、伴有狭窄的退变运动节段以及椎体滑脱且非手术治疗失败的患者,由1名外科医生在2个中心进行了内镜下经椎间孔减压及椎间融合术。观察指标如下:手术时间、术中失血、住院时间、背部和腿部疼痛的视觉模拟评分(VAS)、罗兰 - 莫里斯残疾问卷评分以及术后影像学检查。符合治疗标准的连续系列患者在术前完成了VAS表格和罗兰 - 莫里斯问卷。手术步骤包括关节镜下椎间孔和椎间盘减压;终板准备以及将同种异体骨碎片和骨形态发生蛋白2植入可吸收胶原海绵后植入椎间盘间隙;以及经皮植入椎弓根螺钉。术后,患者再次完成VAS表格和罗兰 - 莫里斯问卷。查阅他们的病历以获取门诊记录、手术记录、住院时间、用药情况和影像学检查结果。对最新的X线和计算机断层扫描片进行回顾和分析。对患者进行至少6个月的随访。查阅文献以比较结果。

结果

60例患者符合纳入标准。平均年龄为52.8岁。病程平均为5年。随访时间为6至25个月,平均为12个月。术前诊断包括椎间盘退变、伴有狭窄的退变运动节段以及椎体滑脱。平均手术时间为2小时54分钟。估计失血量平均为57.6毫升。平均住院时间为2.6天。术前背部疼痛和腿部疼痛明显减轻(P <.005)。最后一次随访时进行的47项影像学检查,包括X线和计算机断层扫描,显示28例患者(59.6%)融合良好,17例(36.2%)固定稳定,2例(4.2%)椎弓根螺钉周围出现骨质溶解。所有患者的运动功能均有改善,而2例患者抱怨有残留麻木感。此外,8例患者(13%)抱怨腰椎伸展时仍有残留不适。2例患者出现与椎弓根螺钉相关的并发症,需要进行手术。文献回顾显示,在内镜下经椎间孔减压及椎间融合术所研究的大多数参数方面,其表现优于开放性经椎间孔腰椎椎间融合术/后路腰椎椎间融合术、微创经椎间孔腰椎椎间融合术以及极外侧腰椎椎间融合术。

结论

内镜下经椎间孔腰椎减压、椎间融合及经皮椎弓根螺钉内固定术在所有人口统计学特征的患者中均持续产生了令人满意的结果。在大多数研究参数方面,其表现优于其他替代手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53e6/4300894/f7bc827342ea/IJSS-6-2012-04-001-g001.jpg

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