van Zwieten P A
Neth Heart J. 2006 Nov;14(11):381-387.
A survey is presented of the registered non-peptidergic angiotensin II receptor antagonists (AT blockers, ARBs, sartans) and their general properties and similarities. Accordingly, their receptor profile, pharmacokinetic and therapeutic applications are discussed. In addition, attention is paid to the individual characteristics of the AT blockers now available. A few components of this category offer additional potentially beneficial properties, owing to their pharmacological or metabolic characteristics. Such additional properties are critically discussed for eprosartan, losartan, telmisartan and valsartan.
本文介绍了已注册的非肽类血管紧张素II受体拮抗剂（AT阻断剂、ARB类、沙坦类）及其一般特性和相似之处。据此，讨论了它们的受体特征、药代动力学和治疗应用。此外，还关注了目前可用的AT阻断剂的个体特性。由于其药理或代谢特性，该类别的一些成分具有额外的潜在有益特性。对依普罗沙坦、氯沙坦、替米沙坦和缬沙坦的此类额外特性进行了批判性讨论。
