Joo F, Klatzo I
Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
Neurol Res. 1989 Jun;11(2):67-75. doi: 10.1080/01616412.1989.11739865.
The view that cerebral endothelial cells represent the cellular basis of the blood-brain barrier has been generally accepted. The regulation of transport processes operating in the cerebral endothelial cells is currently of great interest. Our knowledge of these regulatory mechanisms is briefly reviewed here with special regard to the molecular processes involved in the formation of brain oedema and emphasis on new therapeutic means for its prevention.
大脑内皮细胞代表血脑屏障的细胞基础这一观点已被普遍接受。目前，人们对大脑内皮细胞中运行的转运过程的调节非常感兴趣。在此简要回顾我们对这些调节机制的认识，特别关注与脑水肿形成相关的分子过程，并着重介绍预防脑水肿的新治疗方法。
