Bhatia Smita
Department of Population Sciences, City of Hope National Medical Center, Duarte, CA.
Hematology Am Soc Hematol Educ Program. 2014 Dec 5;2014(1):495-503. doi: 10.1182/asheducation-2014.1.495. Epub 2014 Nov 18.
Survivors of allogeneic hematopoietic cell transplantation (HCT) are at risk of developing long-term complications such as subsequent malignancies and cardiopulmonary compromise. The prevalence of chronic health conditions approaches 75% among allogeneic HCT survivors and that for severe or life-threatening conditions exceeds 20%. This chapter describes the burden of morbidity carried by HCT survivors to help healthcare providers and policy makers understand the scope of the problem and the need for life-long follow-up and proactive care for this vulnerable population.
异基因造血细胞移植(HCT)幸存者面临着出现长期并发症的风险,如后续发生恶性肿瘤和心肺功能受损。在异基因HCT幸存者中,慢性健康状况的患病率接近75%,而严重或危及生命状况的患病率超过20%。本章描述了HCT幸存者所承受的发病负担,以帮助医疗服务提供者和政策制定者了解问题的范围,以及对这一弱势群体进行终身随访和积极护理的必要性。