线粒体乙酰辅酶A羧化酶。再喂养大鼠肝脏中动员/激活的时间进程。
Mitochondrial acetyl-CoA carboxylase. Time course of mobilization/activation in liver of refed rats.
作者信息
Roman-Lopez C R, Shriver B J, Joseph C R, Allred J B
机构信息
Department of Food Science and Nutrition, Ohio State University, Columbus 43210.
出版信息
Biochem J. 1989 Jun 15;260(3):927-30. doi: 10.1042/bj2600927.
Abstract
Fasted (48 h) rats were killed at 0, 2, 4, 6, 8, 12, 16, 20 and 24 h after they were refed on a high-carbohydrate diet. An increase in the maximal activity and quantity of cystolic acetyl-CoA carboxylase was found in liver of refed rats after a lag time of about 8 h. The increased quantity of cytosolic enzyme was attributable primarily to mobilization of mitochondrial storage forms and not to substantial increase in the rate of synthesis of acetyl-CoA carboxylase.
摘要
禁食（48小时）的大鼠在重新喂食高碳水化合物饮食后的0、2、4、6、8、12、16、20和24小时被处死。在大约8小时的延迟期后，重新喂食的大鼠肝脏中胞质乙酰辅酶A羧化酶的最大活性和数量增加。胞质酶数量的增加主要归因于线粒体储存形式的动员，而不是乙酰辅酶A羧化酶合成速率的大幅增加。
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