Brokalaki Hero, Patelarou Evridiki, Giakoumidakis Konstantinos, Kollia Zoi, Fotos Nikolaos V, Vivilaki Victoria, Brokalaki Eirini, Chatzistamatiou Evaggelos, Kallikazaros Ioannis E
Faculty of Nursing, National and Kapodistrian University of Athens, Greece.
Hellenic J Cardiol. 2015 Jan-Feb;56(1):10-9.
The Minnesota Living with Heart Failure Questionnaire (MLHFQ) is an important measurement instrument for assessing the health-related quality of life (HRQOL) among heart failure patients. The purpose of this study was to translate and validate the MLHFQ in the Greek language.
Three hundred forty-four consecutive adult patients from three General Hospitals, two in Athens and one in another part of the country, who were diagnosed with chronic heart failure, and 347 healthy controls were enrolled in the study from March 2009 to March 2010. The questionnaire instrument was translated from English, back-translated, and reviewed by a committee of experts. The psychometric measurements that were performed included reliability coefficients and Explanatory Factor Analysis (EFA), using a Varimax rotation and Principal Components Method. In a further step, confirmatory analysis (CFA)--known as structural equation modeling--of the principal components was conducted.
The internal consistency of the Greek MLHFQ version was found to be 0.97, using Cronbach's alpha coefficient. An exploratory factor analysis identified two domains that accounted for 72.5% of the variance of MLHFQ items; the area under the ROC curve was calculated at 0.942 and the logistic estimate for the threshold score of 24.50 provided the model with 95.1% sensitivity and 99.8% specificity. Additionally, the CFA demonstrated that the two-factor model offered a very good fit to our data.
Our data indicate that the Greek MLHFQ is a reliable and valid tool for assessing HRQOL among patients with heart failure. Health professionals can use it in their clinical practice to improve their evaluation of these patients.
明尼苏达心力衰竭生活质量问卷（MLHFQ）是评估心力衰竭患者健康相关生活质量（HRQOL）的重要测量工具。本研究的目的是将MLHFQ翻译成希腊语并进行验证。
2009年3月至2010年3月，从三家综合医院连续招募了344名成年患者，其中两家在雅典，一家在该国其他地区，这些患者被诊断为慢性心力衰竭，同时招募了347名健康对照者。问卷工具从英语翻译过来，进行回译，并由专家委员会进行审核。所进行的心理测量包括可靠性系数和探索性因子分析（EFA），采用方差最大化旋转和主成分法。进一步对主成分进行验证性分析（CFA）——即结构方程建模。
使用克朗巴赫α系数，发现希腊语版MLHFQ的内部一致性为0.97。探索性因子分析确定了两个领域，它们占MLHFQ项目方差的72.5%；ROC曲线下面积计算为0.942，阈值分数24.50的逻辑估计为模型提供了95.1%的敏感性和99.8%的特异性。此外，CFA表明两因素模型与我们的数据拟合得非常好。
我们的数据表明，希腊语版MLHFQ是评估心力衰竭患者HRQOL的可靠且有效的工具。卫生专业人员可以在临床实践中使用它来改进对这些患者的评估。
