Saito Junichi, Noguchi Satoko, Matsumoto Anna, Jinushi Kei, Kasai Toshinori, Kudo Tomoyuki, Sawada Masahiro, Kimura Futoshi, Kushikata Tetsuya, Hirota Kazuyoshi
Department of Anesthesiology, Hirosaki University Graduate School of Medicine, Hirosaki, 036-8562, Japan,
J Anesth. 2015 Aug;29(4):487-91. doi: 10.1007/s00540-015-1989-9. Epub 2015 Feb 22.
Robot-assisted laparoscopic prostatectomy (RALP) is being increasingly used. However, a steep Trendelenburg position and pneumoperitoneum during RALP has an impact on the respiratory, cardiovascular and cerebrovascular systems. To prevent complications, restrictive fluid management and blood withdrawal have been utilized in our hospital. We examined differences in the anesthetic management between RALP and radical retropubic prostatectomy (RRP), and the efficacy of blood withdrawal.
Medical records of patients who underwent radical prostatectomy in our hospital between January 2012 and October 2013 were retrospectively reviewed. Demographic data, intraoperative blood and fluid administration, perioperative complications and the length of hospital stay were compared among patients receiving RRP, and those receiving RALP with and without blood withdrawal (n = 78, 46 and 68, respectively).
Patients receiving RALP with and without blood withdrawal received a smaller volume of crystalloid during surgery than those receiving RRP (mean ± SD, 5.8 ± 2.3 and 4.2 ± 1.6 vs 14.3 ± 4.1 ml/kg/h, p < 0.001). Median estimated blood loss was 885 g (80-2,800 g) for RRP and 50 g for RALP (3-950 g and 3-550 g, respectively), p < 0.001. None of the patients undergoing RALP received red blood cells, but three patients undergoing RRP did so. RALP with blood withdrawal reduced postoperative hospital stay by 45 % (6 vs 11 days). Four patients receiving RALP without blood withdrawal had delayed extubation due to severe laryngeal edema, which did not occur in any of the patients receiving RALP who had blood withdrawal. Renal function did not differ among the groups.
RALP was associated with less blood loss, no allogeneic transfusion and shorter postoperative hospital stay. This study indicated that blood withdrawal could prevent severe laryngeal edema.
机器人辅助腹腔镜前列腺切除术(RALP)的应用日益广泛。然而,RALP过程中采用的深头低脚位和气腹会对呼吸、心血管及脑血管系统产生影响。为预防并发症,我院采用了限制性液体管理和血液回输。我们研究了RALP与耻骨后根治性前列腺切除术(RRP)在麻醉管理上的差异以及血液回输的效果。
回顾性分析2012年1月至2013年10月在我院接受根治性前列腺切除术患者的病历。比较接受RRP、接受有或无血液回输的RALP患者(分别为n = 78、46和68例)的人口统计学数据、术中血液及液体输注情况、围手术期并发症及住院时间。
接受有或无血液回输的RALP患者术中晶体液输入量少于接受RRP的患者(均值±标准差,5.8±2.3和4.2±1.6 vs 14.3±4.1 ml/kg/h,p < 0.001)。RRP的估计失血量中位数为885 g(80 - 2800 g),RALP为50 g(分别为3 - 950 g和3 - 550 g),p < 0.001。接受RALP的患者均未输注红细胞,但接受RRP的有3例患者输注了。有血液回输的RALP使术后住院时间缩短45%(6天vs 11天)。四名接受无血液回输RALP的患者因严重喉水肿延迟拔管,而接受有血液回输RALP的患者均未出现此情况。各组间肾功能无差异。
RALP与更少的失血量、无需异体输血及更短的术后住院时间相关。本研究表明血液回输可预防严重喉水肿。