Ansell Emily B, Wright Aidan G C, Markowitz John C, Sanislow Charles A, Hopwood Christopher J, Zanarini Mary C, Yen Shirley, Pinto Anthony, McGlashan Thomas H, Grilo Carlos M
Department of Psychiatry, Yale University School of Medicine.
Department of Psychology, University of Pittsburgh.
Personal Disord. 2015 Apr;6(2):161-7. doi: 10.1037/per0000089. Epub 2015 Feb 23.
Identifying personality disorder (PD) risk factors for suicide attempts is an important consideration for research and clinical care alike. However, most prior research has focused on single PDs or categorical PD diagnoses without considering unique influences of different PDs or of severity (sum) of PD criteria on the risk for suicide-related outcomes. This has usually been done with cross-sectional or retrospective assessment methods. Rarely are dimensional models of PDs examined in longitudinal, naturalistic prospective designs. In addition, it is important to consider divergent risk factors in predicting the risk of ever making a suicide attempt versus the risk of making an increasing number of attempts within the same model. This study examined 431 participants who were followed for 10 years in the Collaborative Longitudinal Personality Disorders Study. Baseline assessments of personality disorder criteria were summed as dimensional counts of personality pathology and examined as predictors of suicide attempts reported at annual interviews throughout the 10-year follow-up period. We used univariate and multivariate zero-inflated Poisson regression models to simultaneously evaluate PD risk factors for ever attempting suicide and for increasing numbers of attempts among attempters. Consistent with prior research, borderline PD was uniquely associated with ever attempting. However, only narcissistic PD was uniquely associated with an increasing number of attempts. These findings highlight the relevance of both borderline and narcissistic personality pathology as unique contributors to suicide-related outcomes.
识别自杀未遂的人格障碍(PD)风险因素对研究和临床护理而言都是一项重要考量。然而,大多数先前的研究都聚焦于单一的人格障碍或分类性人格障碍诊断,而未考虑不同人格障碍或人格障碍标准的严重程度(总和)对自杀相关结局风险的独特影响。这通常是通过横断面或回顾性评估方法来完成的。在纵向、自然主义前瞻性设计中很少对人格障碍的维度模型进行检验。此外,在同一模型中预测曾经有过自杀未遂风险与多次自杀未遂风险时,考虑不同的风险因素很重要。本研究对协作纵向人格障碍研究中随访10年的431名参与者进行了考察。人格障碍标准的基线评估被汇总为人格病理学的维度计数,并作为在10年随访期间年度访谈中报告的自杀未遂的预测因素进行检验。我们使用单变量和多变量零膨胀泊松回归模型,同时评估曾经试图自杀以及自杀未遂者中自杀未遂次数增加的人格障碍风险因素。与先前的研究一致,边缘型人格障碍与曾经试图自杀有独特关联。然而,只有自恋型人格障碍与自杀未遂次数增加有独特关联。这些发现凸显了边缘型和自恋型人格病理学作为自杀相关结局的独特促成因素的相关性。